Evidence map›Paper›PMID 33922270›Full record

ArticleEntropy (Basel, Switzerland)2021

Exploring the Alterations in the Distribution of Neural Network Weights in Dementia Due to Alzheimer's Disease.

Marcos Revilla-Vallejo, Jesús Poza, Javier Gomez-Pilar, Roberto Hornero, Miguel Ángel Tola-Arribas, Mónica Cano, Carlos Gómez

Open access · goldAbstract read
In one paragraph

Article in Entropy (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Diagnostic utility of electrophysiological markers for early and differential diagnosis of Alzheimer's, Frontotemporal, and Lewy Body dementias: A systematic review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Pooled it
  2. Entropy in Brain Networks.Entropy (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Marcos Revilla-VallejoBiomedical Engineering Group, E.T.S.I. de Telecomunicación, University of Valladolid, 47011 Valladolid, Spain.ORCID 0000-0002-9873-4891
Jesús PozaBiomedical Engineering Group, E.T.S.I. de Telecomunicación, University of Valladolid, 47011 Valladolid, Spain.ORCID 0000-0001-8577-9559
Javier Gomez-PilarBiomedical Engineering Group, E.T.S.I. de Telecomunicación, University of Valladolid, 47011 Valladolid, Spain.ORCID 0000-0001-7882-7890
Roberto HorneroBiomedical Engineering Group, E.T.S.I. de Telecomunicación, University of Valladolid, 47011 Valladolid, Spain.ORCID 0000-0001-9915-2570
Miguel Ángel Tola-ArribasCentro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina, (CIBER-BBN), 28029 Madrid, Spain.ORCID 0000-0003-4105-0998
Mónica CanoDepartment of Clinical Neurophysiology, Río Hortega University Hospital, 47012 Valladolid, Spain.
Carlos GómezBiomedical Engineering Group, E.T.S.I. de Telecomunicación, University of Valladolid, 47011 Valladolid, Spain.ORCID 0000-0002-9488-0605
Universidad de Valladolid · ESBiomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine · ESHospital Universitario Río Hortega · ES

Funding

Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina CB19/01/00012European Commission 0378_AD_EEGWA_2_PEuropean Commission 0702_MIGRAINEE_2_EEuropean Regional Development Fund 0378_AD_EEGWA_2_PEuropean Regional Development Fund 0702_MIGRAINEE_2_EEuropean Regional Development Fund PGC2018-098214-A-I00Ministerio de Ciencia, Innovación y Universidades PGC2018-098214-A-I00
6 · The paper itself

Abstract

Alzheimer's disease (AD) is a neurodegenerative disorder which has become an outstanding social problem. The main objective of this study was to evaluate the alterations that dementia due to AD elicits in the distribution of functional network weights. Functional connectivity networks were obtained using the orthogonalized Amplitude Envelope Correlation (AEC), computed from source-reconstructed resting-state eletroencephalographic (EEG) data in a population formed by 45 cognitive healthy elderly controls, 69 mild cognitive impaired (MCI) patients and 81 AD patients. Our results indicated that AD induces a progressive alteration of network weights distribution; specifically, the Shannon entropy (SE) of the weights distribution showed statistically significant between-group differences (

Indexed as

Alzheimer’s disease (AD)electroencephalogram (EEG)functional neural networkmild cognitive impairment (MCI)network weights distributionShannon entropy (SE)

Identifiers

PMID33922270
PMCPMC8146430
OpenAlexW3153962284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.