ArticleMarine drugs2021
The Kinetics of Chitosan Degradation in Organic Acid Solutions.
Article in Marine drugs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 59 citations in OpenAlex.
- Collagen-Enriched Immunomodulatory Hydrogel for Tendon Regeneration.Gels (Basel, Switzerland) · 2026Article
- Natural Polymers in Tissue Engineering and Regeneration: Material-Cell Mechanotransduction, Biofabrication Strategies, and Clinical Translation.Biomedicines · 2026Review
- Interfacial Phenomena of Cotton/Polyester Blended Fabric Modified with Enzyme and Chitosan.Polymers · 2026Article
- Alteration in Photosynthetic and Yield Parameters, Content of Metabolites, and Antioxidant Activity of Pepper (Molecules (Basel, Switzerland) · 2025Article
- Effect of Organic Acid Selection on the Physicochemical Properties, Bioadhesion, and Stability of Chitosan Hydrogels.Gels (Basel, Switzerland) · 2025Article
- The Use of Chitosan/Perlite Material for Microbial Support in Anaerobic Digestion of Food Waste.Materials (Basel, Switzerland) · 2025Article
- N-succinyl-chitosan as ecofriendly pesticide carriers: Nano encapsulation and synergistic antifungal effect on 4-hydroxyphenyl-2-propenyl-1-one derivatives based on chalcone structure.Journal of advanced research · 2025Article
- The Functionalization of Activated Polyester Fabrics with Chitosan-Changes in Zeta Potential and Moisture Management.Materials (Basel, Switzerland) · 2024Article
- Oxidative degradation of chitosan by Fe-MCM-41 heterogeneous Fenton-like system.Scientific reports · 2024Article
- Bio-Innovative Modification of Poly(Ethylene Terephthalate) Fabric Using Enzymes and Chitosan.Polymers · 2024Article
- Synthesis and Characterization of Antibacterial Chitosan Films with Ciprofloxacin in Acidic Conditions.International journal of molecular sciences · 2023Article
- Review
- Article
- Recent Application Prospects of Chitosan Based Composites for the Metal Contaminated Wastewater Treatment.Polymers · 2023Review
- A CS-based composite scaffold with excellent photothermal effect and its application in full-thickness skin wound healing.Regenerative biomaterials · 2023Article
- A Novel Method of Endotoxins Removal from Chitosan Hydrogel as a Potential Bioink Component Obtained by COInternational journal of molecular sciences · 2022Article
- Article
- Mechanism and Application of Chitosan and Its Derivatives in Promoting Permeation in Transdermal Drug Delivery Systems: A Review.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Biodegradable microneedle patch for delivery of meloxicam for managing pain in cattle.PloS one · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper presents a comparative study on chitosan degradation in organic acid solutions according to their different dissociation characteristics. More precisely, the aim of the study was to determine the kinetics of the degradation process depending on the different acid dissociation constants (pKa values). The scientists involved in chitosan to date have focused mainly on acetic acid solutions. Solutions of lactic, acetic, malic, and formic acids in concentrations of 3% wt. were used in this research. The progress of degradation was determined based on the intrinsic viscosity measurement, GPC/SEC chromatographic analysis, and their correlation. Changes in the viscosity parameters were performed at a temperature of 20 °C ± 1 °C and a timeframe of up to 168 h (7 days). The chemical structure and DDA of the initial chitosan were analyzed using 1H-NMR spectroscopy analysis. The results of this study can be considered of high importance for the purpose of electrospinning, production of micro- and nano-capsules for drug delivery, and other types of processing. Understanding the influence of the dissociation constant of the solvent on the kinetics of chitosan degradation will allow the selection of an appropriate medium, ensuring an effective and stable spinning process, in which the occurrence of polymer degradation is unfavorable.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.