Evidence map›Paper›PMID 33922212›Full record

ArticleBiomedicines2021

Translational Attenuation by an Intron Retention in the 5' UTR of

Youn Jung Kim, Yejin Lee, Hong Zhang, John Timothy Wright, James P Simmer, Jan C-C Hu, Jung-Wook Kim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Expression ofInternational journal of molecular sciences · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Youn Jung KimDepartment of Molecular Genetics & DRI, School of Dentistry, Seoul National University, Seoul 03080, Korea.
Yejin LeeDepartment of Pediatric Dentistry & DRI, School of Dentistry, Seoul National University, Seoul 03080, Korea.
Hong ZhangDepartment of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, MI 48108, USA.ORCID 0000-0003-4558-9026
John Timothy WrightDivision of Pediatric & Public Health Dentistry, School of Dentistry, University of North Carolina, Chapel Hill, NC 27514, USA.
James P SimmerDepartment of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, MI 48108, USA.
Jan C-C HuDepartment of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, MI 48108, USA.
Jung-Wook KimDepartment of Molecular Genetics & DRI, School of Dentistry, Seoul National University, Seoul 03080, Korea.ORCID 0000-0002-9399-2197
Seoul National University · KRUniversity of Michigan · USUniversity of North Carolina at Chapel Hill · US

Funding

Proteomics and Genetics of Enamel and DentinR01DE015846 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HU, JAN CHING CHUN · 2004 to 2019
$5.7M
Genetic Mechanisms of Amelogenesis ImperfectaR56DE015846 · NIDCR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HU, JAN CHING CHUN · 2021 to 2021
$402k
National Research Foundation of Korea NRF-2018R1A5A2024418National Research Foundation of Korea NRF-2020R1A2C2100543NIDCR NIH HHS DE015846
6 · The paper itself

Abstract

Amelogenesis imperfecta (AI) is a collection of rare genetic conditions affecting tooth enamel. The affected enamel can be of insufficient quantity and/or altered quality, impacting structural content, surface integrity and coloration. Heterozygous mutations in

Indexed as

amelogenesis imperfectaENAMhereditary enamel defectsintron retentionsplicing donor site mutationwhole exome sequencing

Identifiers

PMID33922212
PMCPMC8145330
OpenAlexW3158739158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.