ReviewNanomaterials (Basel, Switzerland)2021
Applications and Biological Activity of Nanoparticles of Manganese and Manganese Oxides in In Vitro and In Vivo Models.
Review in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
24 citing papers in PubMed, 74 citations in OpenAlex.
- Molecular Mechanisms of Manganese Oxide Nanoparticles Toxicity in Brain and Other Tissues: An Overview.Frontiers in bioscience (Landmark edition) · 2026Review
- Microglia encapsulation in nanozyme-loaded hydrogels: response to oxidative stress and inflammation.Nanomedicine (London, England) · 2026Article
- MnAntioxidants (Basel, Switzerland) · 2026Article
- Phytotoxic and Eustress Effects of Metal Oxide Nanoparticles (CuO, MnPlants (Basel, Switzerland) · 2026Review
- Nanoengineered γ MnOLife (Basel, Switzerland) · 2026Article
- Integrated GC-MS Profiling and Phytosynthesis of MnOChemistry & biodiversity · 2026Article
- Article
- Engineering Nanomaterial Platform for Inflammatory Bowel Disease: Three-Dimensional Integration of Delivery Mechanism, Therapeutic Drug Delivery and Intelligent Material Design.International journal of nanomedicine · 2026Review
- Consequences of Dietary Manganese Deficiency or MnNutrients · 2025Article
- Article
- Interaction of Manganese-Doped Copper Oxide Nano-Platelets with Cells: Biocompatibility and Anticancer Activity Assessment.Biomimetics (Basel, Switzerland) · 2025Article
- Comparative study on structural, morphological, and optical properties of MS/Fe3O4 nanocomposites and M-doped Fe3O4 nanopowders (M = Mn, Zn).Scientific reports · 2024Article
- Metabolic Derangement of Essential Transition Metals and Potential Antioxidant Therapies.International journal of molecular sciences · 2024Review
- Characterization and Cellular Toxicity Studies of Commercial Manganese Oxide Nanoparticles.Nanomaterials (Basel, Switzerland) · 2024Article
- Inorganic Nanoparticle Functionalization Strategies in Immunotherapeutic Applications.Biomaterials research · 2024Review
- Effect of Melissa officinalis L. leaf extract on manganese-induced cyto-genotoxicity on Allium cepa L.Scientific reports · 2023Article
- Transcriptomics-based investigation of manganese dioxide nanoparticle toxicity in rats' choroid plexus.Scientific reports · 2023Article
- Comparative Evaluation of the Cytotoxic Effects of Metal Oxide and Metalloid Oxide Nanoparticles: An Experimental Study.International journal of molecular sciences · 2023Article
- Smart Biomimetic Nanozymes for Precise Molecular Imaging: Application and Challenges.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Aerosolised micro and nanoparticle: formulation and delivery method for lung imaging.Clinical and translational imaging · 2023Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The expanding applications of nanotechnology seem to be a response to many technological, environmental, and medical challenges. The unique properties of nanoparticles allow for developing new technologies and therapies. Among many investigated compounds is manganese and its oxides, which in the form of nanoparticles, could be a promising alternative for gadolinium-based contrast agents used in diagnostic imaging. Manganese, which is essential for living organisms as an enzyme cofactor, under excessive exposure-for example, due to water contamination or as an occupational hazard for welders-can lead to neurological disorders, including manganism-a condition similar to Parkinson's disease. This review attempts to summarise the available literature data on the potential applications of manganese and manganese oxide nanoparticles and their biological activity. Some of the published studies, both in vitro and in vivo, show negative effects of exposure to manganese, mainly on the nervous system, whereas other data suggest that it is possible to develop functionalised nanoparticles with negligible toxicity and novel promising properties.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.