Evidence map›Paper›PMID 33922028›Full record

ArticleBiosensors2021

A Novel Fluorescent Probe for Selective Detection of Hydrazine and Its Application in Imaging.

Ruo-Jun Man, Meng-Ke Wu, Bing Yang, Yu-Shun Yang

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ruo-Jun ManGuangxi Biological Polysaccharide Separation, Purification and Modification Research Platform, Guangxi University for Nationalities, Nanning 530006, China.
Meng-Ke WuGuangxi Biological Polysaccharide Separation, Purification and Modification Research Platform, Guangxi University for Nationalities, Nanning 530006, China.
Bing YangSchool of Chemistry and Chemical Engineering, Nantong University, Nantong 226019, China.
Yu-Shun YangResearch Centre of Sensors and Functional Materials, Hi-Techjig Co. Ltd., Zhenjiang 212415, China.
Guangxi University for Nationalities · CNNantong University · CN

Funding

Guangxi University for Nationalities Research Funded Project 2018KJQD13Large Instruments Open Foundation of Nantong University KBJN2024Nantong University Scientific Research Foundation for the Introduced Talents 03081220Natural Science Foundation of Guangxi Province 2019AC20294Natural Science Foundation of Guangxi Province 2020GXNSFBA238021Specific Research Project of Guangxi for Research Bases and Talents Gui Ke AD20159070
6 · The paper itself

Abstract

In this work, a novel fluorescent probe with first-time-selected thiazepine backbone, TZPzine-1, was developed for selective detection of hydrazine in water samples and living cells. Chosen from our recent anti-cancer agents, TZPzine-1 inferred structurally based advantages of the optical adjustability and the hydrazine-trapping approach. It also showed applicable properties including high sensitivity (LOD = 50 nM), wide linear range (0-15 equiv.), high selectivity (especially from competing species), rapid response (within 20 min), and practical steadiness in various pH (6.0-11.0) and temperature (15-50 °C) conditions. To satisfy the interdisciplinary requirements in environmental toxicology, TZPzine-1 was successfully applied in water samples and living cells. We hope that the information in this work, as well as the concept of monitoring the nitrogen cycle, may be referable for future research on systematic management.

Indexed as

Fluorescent DyesHeLa CellsHumansHydrazinesSpectrometry, FluorescenceFluorescent DyeshydrazineHydrazinesbiological imagingfluorescent probehydrazine detectionthiazepine moietywater samples

Identifiers

PMID33922028
PMCPMC8143562
OpenAlexW3156917885

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.