Evidence map›Paper›PMID 33922004›Full record

ReviewNanomaterials (Basel, Switzerland)2021

Nanobiosystems for Antimicrobial Drug-Resistant Infections.

Foteini Gkartziou, Nikolaos Giormezis, Iris Spiliopoulou, Sophia G Antimisiaris

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  13. Phage therapeutics: from promises to practices and prospectives.Applied microbiology and biotechnology · 2021
    Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Foteini GkartziouInstitute of Chemical Engineering, FORTH/ICES, Platani, 26504 Patras, Greece.
Nikolaos GiormezisNational Reference Centre for Staphylococci, School of Medicine, University of Patras, 26504 Patras, Greece.
Iris SpiliopoulouNational Reference Centre for Staphylococci, School of Medicine, University of Patras, 26504 Patras, Greece.
Sophia G AntimisiarisInstitute of Chemical Engineering, FORTH/ICES, Platani, 26504 Patras, Greece.ORCID 0000-0002-2312-5848

Funding

European Social Fund-ESF) through the Operational Programme «Human Resources Development, Education and Lifelong Learning 2014-2020» in the context of the project "Innovative lipid nanoparticles for treatment of staphylococcal biomembranes" (MIS 5049223). MIS 5049223
6 · The paper itself

Abstract

The worldwide increased bacterial resistance toward antimicrobial therapeutics has led investigators to search for new therapeutic options. Some of the options currently exploited to treat drug-resistant infections include drug-associated nanosystems. Additionally, the use of bacteriophages alone or in combination with drugs has been recently revisited; some studies utilizing nanosystems for bacteriophage delivery have been already reported. In this review article, we focus on nine pathogens that are the leading antimicrobial drug-resistant organisms, causing difficult-to-treat infections. For each organism, the bacteriophages and nanosystems developed or used in the last 20 years as potential treatments of pathogen-related infections are discussed. Summarizing conclusions and future perspectives related with the potential of such nano-antimicrobials for the treatment of persistent infections are finally highlighted.

Indexed as

antimicrobial resistancebacteriophagedruginfectious diseaseliposomesMRSAnanoparticle

Identifiers

PMID33922004
PMCPMC8143556

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.