ArticleInternational journal of molecular sciences2021
Micro-Current Stimulation Has Potential Effects of Hair Growth-Promotion on Human Hair Follicle-Derived Papilla Cells and Animal Model.
Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 33 citations in OpenAlex.
- Preliminary Effects of Hyperbaric Oxygen Therapy on Hair Follicle Characteristics in Healthy Subjects.Bioengineering (Basel, Switzerland) · 2026Article
- Application of electrospun piezoelectric nanofibers in wound healing.Burns & trauma · 2026Review
- The Scalp Microbiome-Hair Axis: Mechanisms and Therapeutic Translation.Research (Washington, D.C.) · 2026Review
- Whole-genome selection signatures identified candidate genes associated with cashmere traits in Inner Mongolia cashmere goats.Animal bioscience · 2025Article
- The Clinical Evaluation of Serum WS Biotin, a Novel Encapsulated Form of D-Biotin With Improved Water Solubility, for Anti-Hair Shedding Applications. A Prospective Single-Arm, Nonrandomized, Pretest-Posttest Study.Health science reports · 2025Article
- Novel Electrotrichogenic Device Promotes Hair Growth in Men With Androgenetic Alopecia: A Pilot Study.Journal of cosmetic dermatology · 2025Article
- Exosomes from human umbilical cord mesenchymal stem cells promote the growth of human hair dermal papilla cells.PloS one · 2025Article
- Electrospinning for Mimicking Bioelectric Microenvironment in Tissue Regeneration.Research (Washington, D.C.) · 2025Review
- Hair Growth Promoting Effects of Solubilized Sturgeon Oil and Its Correlation with the Gut Microbiome.Pharmaceuticals (Basel, Switzerland) · 2024Article
- Bioelectric medicine: unveiling the therapeutic potential of micro-current stimulation.Biomedical engineering letters · 2024Review
- Innovative Strategies for Hair Regrowth and Skin Visualization.Pharmaceutics · 2023Review
- Micro-Current Stimulation Can Modulate the Adipogenesis Process by Regulating the Insulin Signaling Pathway in 3T3-L1 Cells andLife (Basel, Switzerland) · 2023Article
- mTOR signaling in hair follicle and hair diseases: recent progress.Frontiers in medicine · 2023Review
- miR-27a TargetingAnimals : an open access journal from MDPI · 2022Article
- Heat-KilledInternational journal of molecular sciences · 2022Article
- Micro-Current Stimulation Suppresses Inflammatory Responses in Peptidoglycan-Treated Raw 264.7 Macrophages andInternational journal of molecular sciences · 2022Article
- Morphogenesis, Growth Cycle and Molecular Regulation of Hair Follicles.Frontiers in cell and developmental biology · 2022Review
- Exosomes Secreted from Adipose-Derived Stem Cells Are a Potential Treatment Agent for Immune-Mediated Alopecia.Journal of immunology research · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Recently, a variety of safe and effective non-pharmacological methods have been introduced as new treatments of alopecia. Micro-current electrical stimulation (MCS) is one of them. It is generally known to facilitate cell proliferation and differentiation and promote cell migration and ATP synthesis. This study aimed to investigate the hair growth-promoting effect of MCS on human hair follicle-derived papilla cells (HFDPC) and a telogenic mice model. We examined changes in cell proliferation, migration, and cell cycle progression with MCS-applied HFDPC. The changes of expression of the cell cycle regulatory proteins, molecules related to the PI3K/AKT/mTOR/Fox01 pathway and Wnt/β-catenin pathway were also examined by immunoblotting. Subsequently, we evaluated the various growth factors in developing hair follicles by RT-PCR in MCS-applied (MCS) mice model. From the results, the MCS-applied groups with specific levels showed effects on HFDPC proliferation and migration and promoted cell cycle progression and the expression of cell cycle-related proteins. Moreover, these levels significantly activated the Wnt/β-catenin pathway and PI3K/AKT/mTOR/Fox01 pathway. Various growth factors in developing hair follicles, including Wnts, FGFs,
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.