Evidence map›Paper›PMID 33921878›Full record

ReviewDiseases (Basel, Switzerland)2021

SARS-CoV-2 Infection and Risk Management in Multiple Sclerosis.

Amado Diaz de la Fe, Alejandro Armando Peláez Suárez, Marinet Fuentes Campos, Maivis Noemí Cabrera Hernández, Carlos-Alberto Goncalves, Stephen Schultz, Dario Siniscalco, Maria Angeles Robinson-Agramonte

Open access · goldAbstract readReview
In one paragraph

Review in Diseases (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. COVID-19 and the Nervous System from a Cuban Experience.Behavioral sciences (Basel, Switzerland) · 2023
    Review
  3. Review
  4. An Update on the Status of Vaccine Development for SARS-CoV-2 Including Variants. Practical Considerations for COVID-19 Special Populations.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Amado Diaz de la FeNeuromuscular Diseases Clinic, International Center for Neurological Restoration, Habana 11300, Cuba.
Alejandro Armando Peláez SuárezNeuromuscular Diseases Clinic, International Center for Neurological Restoration, Habana 11300, Cuba.ORCID 0000-0003-3137-2897
Marinet Fuentes CamposDepartamento de Medicina Familiar y Comunitaria Policlínico 28 de Enero, Habana 11300, Cuba.
Maivis Noemí Cabrera HernándezConsulta de Alergia, Hospital General Secretaria de Salud, Iguala City 40000, Mexico.
Carlos-Alberto GoncalvesDepartment of Biochemistry, Federal University of Rio Grande do Sul, Porto Alegre 90040-060, Brazil.ORCID 0000-0001-8430-5650
Stephen SchultzDepartment of Cellular and Integrative Physiology, Center for Biomedical Neuroscience, University of Texas (UT) Health Science Center San Antonio, San Antonio, TX 78229, USA.
Dario SiniscalcoDepartment of Experimental Medicine, University of Campania, 80138 Naples, Italy.ORCID 0000-0002-3779-2596
Maria Angeles Robinson-AgramonteNeuroimmunology Department, Research Center, International Center for Neurological Restoration, Habana 11300, Cuba.
International Center of Neurologic Restoration · CUSecretaria de Salud · MXThe University of Texas Health Science Center at San Antonio · USUniversidade Federal do Rio Grande do Sul · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The novel coronavirus can cause a severe respiratory disease with impact on the central nervous system, as has been reported by several medical health services. In the COVID-19 pandemic caused by the SARS-CoV-2 neurotrophic virus, neurologists have focused their attention on the early identification of suggestive manifestations of the neurological impact of the disease. In this context, they are exploring related chronic disease and the possibility of achieving a more effective understanding of symptoms derived from COVID-19 infection and those derived from the course of preexisting neurological disease. The present review summarizes evidence from the infection with SARS-CoV-2 and the management of the risks of multiple sclerosis and how it is related to the risks of general comorbidities associated with COVID-19. In addition, we reviewed other factors characteristic of MS, such as relapses, and the maximum tolerated dose of treatment medications from clinical and experimental evidence.

Indexed as

benefit versus risk in multiple sclerosis (BRMS)COVID-19multiple sclerosis (MS)SARS-CoV-2

Identifiers

PMID33921878
PMCPMC8167598
OpenAlexW3156757076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.