Evidence map›Paper›PMID 33921867›Full record

ArticleJournal of clinical medicine2021

Antithrombotic Management and Long-Term Outcomes of Patients with Atrial Fibrillation. Insights from CRAFT Trial.

Paweł Balsam, Piotr Lodziński, Monika Gawałko, Leszek Kraj, Andrzej Śliwczyński, Cezary Maciejewski, Bartosz Krzowski, Agata Tymińska, Krzysztof Ozierański, Marcin Grabowski and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02987062 (CRAFT - Multicenter Experience in Atrial Fibrillation Patients Treated With OAC), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02987062 unknown statusnot on this map

CRAFT - Multicenter Experience in Atrial Fibrillation Patients Treated With OAC (CRAFT)

TypeobservationalSponsorMedical University of WarsawRan2016 to 2017Enrolled2,000ConditionsAtrial Fibrillation
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Paweł Balsam1st Department of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Piotr Lodziński1st Department of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Monika Gawałko1st Department of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0003-4619-9062
Leszek KrajDepartment of Oncology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Andrzej ŚliwczyńskiSatellite Campus in Warsaw, University of Humanities and Economics in Łódź, 90-212 Łódź, Poland.
Cezary Maciejewski1st Department of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0003-2619-7190
Bartosz Krzowski1st Department of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0001-9987-870X
Agata Tymińska1st Department of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0003-1381-302X
Krzysztof Ozierański1st Department of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Marcin Grabowski1st Department of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.ORCID 0000-0003-3306-0301
Janusz BednarskiCardiology Unit, St. John Paul II Western Hospital, 05-825 Grodzisk Mazowiecki, Poland.
Grzegorz Opolski1st Department of Cardiology, Medical University of Warsaw, 02-091 Warsaw, Poland.
Medical University of Warsaw · PLJohn Paul II Hospital · PLUniversity of Humanities and Economics in Lodz · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to compare long-term outcomes in Polish patients with atrial fibrillation (AF) according to oral anticoagulation (OAC) type and to evaluate the predictive value of common thromboembolic and bleeding risk scores.

methodsData from the CRAFT trial (NCT02987062) were included. The primary study endpoint was major adverse event (MAE; all-cause death, thromboembolic and hemorrhagic event) during the mean four-year follow-up period.

resultsOut of 2983 patients with available follow-up data, 1686 (56%) were prescribed with vitamin K antagonist (VKA), 891 (30%) with rivaroxaban and 406 (14%) with dabigatran. Predominance of elderly and female patients with previous history of thromboembolic and hemorrhagic events was observed within rivaroxaban (vs. other OAC) group. Higher rate of MAEs and its components was observed in patients on VKA followed by rivaroxaban as compared to patients on dabigatran (43% vs. 42% vs. 31%,

conclusionsDespite no difference in the thromboembolic event rate, treatment with VKA and rivaroxaban was associated with a significant increase in the risk of hemorrhagic events.

Indexed as

anticoagulationarrhythmiadabigatranrisk scoresrivaroxaban

Identifiers

PMID33921867
PMCPMC8073861
OpenAlexW3156427687

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.