ArticleBrain sciences2021
Morphological and Hemodynamic Changes during Cerebral Aneurysm Growth.
Article in Brain sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 22 citations in OpenAlex.
- Intracranial Aneurysm Wall Phenotypes: Clinical, Morphological, and Hemodynamic Influences.Stroke (Hoboken, N.J.) · 2025Article
- Predictive modeling and machine learning show poor performance of clinical, morphological, and hemodynamic parameters for small intracranial aneurysm rupture.Scientific reports · 2025Article
- Competing pathways of intracranial aneurysm growth: linking regional growth distribution and hemodynamics.Journal of neurosurgery · 2025Article
- Clinical and Hemodynamic Features of Aneurysm Rupture in Coil Embolization of Intracranial Aneurysms.Diagnostics (Basel, Switzerland) · 2024Article
- Article
- Hemodynamic differences determining rupture and non-rupture in middle cerebral aneurysms after growth.PloS one · 2024Article
- Computational Fluid Dynamics Analysis Features in Aneurysm Development in Rats.Neurologia medico-chirurgica · 2023Article
- Image-derived Metrics Quantifying Hemodynamic Instability Predicted Growth of Unruptured Intracranial Aneurysms.Stroke (Hoboken, N.J.) · 2023Article
- Cerebral aneurysms at major arterial bifurcations are associated with the arterial branch forming a smaller angle with the parent artery.Scientific reports · 2022Article
- Different Hemodynamic Characteristics and Resulting in Different Risks of Rupture Between Wide-Neck and Narrow-Neck Aneurysms.Frontiers in neurology · 2022Article
- Hemodynamic Characteristic Analysis of Aneurysm Wall Enhancement in Unruptured Middle Cerebral Artery Aneurysm.Frontiers in neurology · 2022Article
- Computer-Assisted Aneurysm Growth Evaluation and Detection (AGED): Comparison with Clinical Aneurysm Follow-Up.Journal of blood disorders & transfusion · 2022Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
Abstract
Computational fluid dynamics (CFD) has grown as a tool to help understand the hemodynamic properties related to the rupture of cerebral aneurysms. Few of these studies deal specifically with aneurysm growth and most only use a single time instance within the aneurysm growth history. The present retrospective study investigated four patient-specific aneurysms, once at initial diagnosis and then at follow-up, to analyze hemodynamic and morphological changes. Aneurysm geometries were segmented via the medical image processing software Mimics. The geometries were meshed and a computational fluid dynamics (CFD) analysis was performed using ANSYS. Results showed that major geometry bulk growth occurred in areas of low wall shear stress (WSS). Wall shape remodeling near neck impingement regions occurred in areas with large gradients of WSS and oscillatory shear index. This study found that growth occurred in areas where low WSS was accompanied by high velocity gradients between the aneurysm wall and large swirling flow structures. A new finding was that all cases showed an increase in kinetic energy from the first time point to the second, and this change in kinetic energy seems correlated to the change in aneurysm volume.
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Registered trials
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