Evidence map›Paper›PMID 33921798›Full record

ArticleMolecules (Basel, Switzerland)2021

Quinazoline Derivatives Designed as Efflux Pump Inhibitors: Molecular Modeling and Spectroscopic Studies.

Ana-Maria Udrea, Andra Dinache, Jean-Marie Pagès, Ruxandra Angela Pirvulescu

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Spectroscopic Analysis of the TiOInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ana-Maria UdreaLaser Department, National Institute for Laser, Plasma and Radiation Physics, Magurele, 077125 Ilfov, Romania.ORCID 0000-0002-7659-7435
Andra DinacheLaser Department, National Institute for Laser, Plasma and Radiation Physics, Magurele, 077125 Ilfov, Romania.ORCID 0000-0001-6107-7675
Jean-Marie PagèsUMR-MD1, U1261, Aix-Marseille Univ, INSERM, SSA, MCT, 13385 Marseille, France.ORCID 0000-0001-7092-7977
Ruxandra Angela PirvulescuDepartment of Ophthalmology, University of Medicine and Pharmacy Carol Davila, 020022 Bucharest, Romania.

Funding

Romanian National Authority for Scientific Research and Innovation, CNCS/CCCDI-UEFISCDI Nucleu Programme, ctr. No. 16N /08.02.2019Romanian National Authority for Scientific Research and Innovation, CNCS/CCCDI-UEFISCDI PN-III-P1-1.1-PCCDI-2017-0728Romanian National Authority for Scientific Research and Innovation, CNCS/CCCDI-UEFISCDI PN-III-P2-2.1-PED-2019-1264Romanian National Authority for Scientific Research and Innovation, CNCS/CCCDI-UEFISCDI PN-III-P2-2.1-PED-2019-4771Romanian National Authority for Scientific Research and Innovation, CNCS/CCCDI-UEFISCDI PN-III-P2-2.1-PED-2019-5283
6 · The paper itself

Abstract

Multidrug resistance of bacteria is a worrying concern in the therapeutic field and an alternative method to combat it is designing new efflux pump inhibitors (EPIs). This article presents a molecular study of two quinazoline derivatives, labelled BG1189 and BG1190, proposed as EPIs.

Indexed as

Anti-Bacterial AgentsModels, MolecularMolecular Docking SimulationQuinazolinesSpectroscopy, Fourier Transform InfraredAnti-Bacterial AgentsQuinazolinesAcrAB-TolC pumpefflux pump inhibitorFTIR spectroscopymolecular dockingmultidrug resistance (MDR)quinazolineUV-Vis spectroscopy

Identifiers

PMID33921798
PMCPMC8073189

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.