Evidence map›Paper›PMID 33921788›Full record

ArticleInternational journal of molecular sciences2021

Biochemical and Biophysical Characterization of Recombinant Human 3-Phosphoglycerate Dehydrogenase.

Giulia Murtas, Giorgia Letizia Marcone, Alessio Peracchi, Erika Zangelmi, Loredano Pollegioni

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  4. A crucial active site network of titratable residues guides catalysis and NADProtein science : a publication of the Protein Society · 2025
    Article
  5. On the quaternary structure of human D-3-phosphoglycerate dehydrogenase.Protein science : a publication of the Protein Society · 2024
    Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Giulia MurtasDepartment of Biotechnology and Life Sciences, University of Insubria, via J.H. Dunant 3, 21100 Varese, Italy.ORCID 0000-0002-9086-5520
Giorgia Letizia MarconeDepartment of Biotechnology and Life Sciences, University of Insubria, via J.H. Dunant 3, 21100 Varese, Italy.ORCID 0000-0002-4650-9449
Alessio PeracchiDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, Italy.ORCID 0000-0003-3254-4099
Erika ZangelmiDepartment of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, 43124 Parma, Italy.ORCID 0000-0001-9960-8144
Loredano PollegioniDepartment of Biotechnology and Life Sciences, University of Insubria, via J.H. Dunant 3, 21100 Varese, Italy.
University of Insubria · ITUniversity of Parma · IT

Funding

Ministero dell'Università e della Ricerca Scientifica Grant 2017H4J3AS
6 · The paper itself

Abstract

The human enzyme D-3-phosphoglycerate dehydrogenase (hPHGDH) catalyzes the reversible dehydrogenation of 3-phosphoglycerate (3PG) into 3-phosphohydroxypyruvate (PHP) using the NAD

Indexed as

Carboxylic AcidsEscherichia coliGlycineHumansKineticsNADPhosphoglycerate DehydrogenaseReceptors, N-Methyl-D-AspartateSerineCarboxylic AcidsGlycineNADPhosphoglycerate DehydrogenaseReceptors, N-Methyl-D-AspartateSerinebiochemical propertiescancer progressionD-serineL-serinemetabolismNADneurotransmissionNMDA receptorphosphorylated pathwayserine deficiency

Identifiers

PMID33921788
PMCPMC8073719
OpenAlexW3154313752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.