Evidence map›Paper›PMID 33921780›Full record

ArticleInternational journal of molecular sciences2021

The Gut Microbiota Affects Corticosterone Production in the Murine Small Intestine.

Peter Ergang, Karla Vagnerová, Petra Hermanová, Martin Vodička, Michal Jágr, Dagmar Šrůtková, Václav Dvořáček, Tomáš Hudcovic, Jiří Pácha

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
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  10. The gut-microbiota-brain axis: Focus on gut steroids.Journal of neuroendocrinology · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Stress and the gut-brain axis: an inflammatory perspective.Frontiers in molecular neuroscience · 2024
    Review
  17. Article
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  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Peter ErgangInstitute of Physiology, Czech Academy of Sciences, CZ-142 20 Prague, Czech Republic.
Karla VagnerováInstitute of Physiology, Czech Academy of Sciences, CZ-142 20 Prague, Czech Republic.
Petra HermanováInstitute of Microbiology, Czech Academy of Sciences, CZ-549 22 Nový Hrádek, Czech Republic.
Martin VodičkaInstitute of Physiology, Czech Academy of Sciences, CZ-142 20 Prague, Czech Republic.
Michal JágrCrop Research Institute, CZ-161 06 Prague, Czech Republic.
Dagmar ŠrůtkováInstitute of Microbiology, Czech Academy of Sciences, CZ-549 22 Nový Hrádek, Czech Republic.
Václav DvořáčekCrop Research Institute, CZ-161 06 Prague, Czech Republic.
Tomáš HudcovicInstitute of Microbiology, Czech Academy of Sciences, CZ-549 22 Nový Hrádek, Czech Republic.
Jiří PáchaInstitute of Physiology, Czech Academy of Sciences, CZ-142 20 Prague, Czech Republic.ORCID 0000-0003-2335-6715
Czech Academy of Sciences · CZCzech Agrifood Research Center · CZ

Funding

Czech Science Foundation 18-02993S, 21-10845S
6 · The paper itself

Abstract

Glucocorticoids (GCs) are hormones that are released in response to stressors and exhibit many activities, including immunomodulatory and anti-inflammatory activities. They are primarily synthesized in the adrenal gland but are also produced in peripheral tissues via regeneration of adrenal 11-oxo metabolites or by

Indexed as

11-beta-Hydroxysteroid DehydrogenasesAnimalsCorticosteroneGastrointestinal MicrobiomeIntestine, SmallMaleMiceReal-Time Polymerase Chain ReactionSteroidsTandem Mass Spectrometry11-beta-Hydroxysteroid DehydrogenasesCorticosteroneSteroids11β-hydroxysteroid dehydrogenaseanti-CD3 antibodyextra-adrenal steroidogenesisglucocorticoidsintestinemicrobiome

Identifiers

PMID33921780
PMCPMC8073041
OpenAlexW3153809368

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.