Evidence map›Paper›PMID 33921777›Full record

ArticleInternational journal of molecular sciences2021

Bee Bread Ameliorates Vascular Inflammation and Impaired Vasorelaxation in Obesity-Induced Vascular Damage Rat Model: The Role of eNOS/NO/cGMP-Signaling Pathway.

Zaidatul Akmal Othman, Zaida Zakaria, Joseph Bagi Suleiman, Victor Udo Nna, Aminah Che Romli, Wan Syaheedah Wan Ghazali, Mahaneem Mohamed

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. Vasorelaxant and Hypotensive Effects ofInternational journal of molecular sciences · 2024
    Article
  2. Article
  3. Therapeutic Effects ofAntioxidants (Basel, Switzerland) · 2022
    Article
  4. Wax apple (Journal of traditional and complementary medicine · 2022
    Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Zaidatul Akmal OthmanDepartment of Physiology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
Zaida ZakariaDepartment of Physiology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.ORCID 0000-0002-4138-4747
Joseph Bagi SuleimanDepartment of Science Laboratory Technology, Akanu Ibiam Federal Polytechnic, P.M.B 1007, Unwana, Ebonyi State, Nigeria.ORCID 0000-0002-0629-7621
Victor Udo NnaDepartment of Physiology, Faculty of Basic Medical Sciences, College of Medical Sciences, University of Calabar, Calabar, P.M.B. 1115, Calabar, Cross River State, Nigeria.ORCID 0000-0001-7616-9468
Aminah Che RomliDepartment of Physiology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
Wan Syaheedah Wan GhazaliDepartment of Physiology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
Mahaneem MohamedDepartment of Physiology, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.ORCID 0000-0001-9333-1957
Universiti Sains Malaysia · MYThe Federal Polytechnic, Ado-Ekiti · NGUniversity of Calabar · NG

Funding

Universiti Sains Malaysia USM/IACUC/2018/(113)(933)
6 · The paper itself

Abstract

Obesity and hyperlipidemia are major risk factors for developing vascular diseases. Bee bread (BB) has been reported to exhibit some biological actions, including anti-obesity and anti-hyperlipidemic. This study aims to investigate whether bee bread can ameliorate vascular inflammation and impaired vasorelaxation activity through eNOS/NO/cGMP pathway in obese rats. Forty male Sprague-Dawley rats were randomly divided into four groups (

Indexed as

AnimalsCyclic GMPDiet, High-FatHyperlipidemiasInflammationMaleNitric OxideNitric Oxide Synthase Type IIINucleotides, CyclicObesityOrlistatPropolisRatsRats, Sprague-DawleySignal TransductionVasodilationCyclic GMPcyclic guanosine monophosphate-adenosine monophosphateNitric OxideNitric Oxide Synthase Type IIINucleotides, CyclicOrlistatPropolisbee breadeNOS/NO/cGMP pathwayhyperlipidemiaobesityvasorelaxation

Identifiers

PMID33921777
PMCPMC8072722
OpenAlexW3156946244

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.