Evidence map›Paper›PMID 33921760›Full record

ReviewJournal of clinical medicine2021

Bone Metastases from Gastric Cancer: What We Know and How to Deal with Them.

Angelica Petrillo, Emilio Francesco Giunta, Annalisa Pappalardo, Davide Bosso, Laura Attademo, Cinzia Cardalesi, Anna Diana, Antonietta Fabbrocini, Teresa Fabozzi, Pasqualina Giordano and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Heterogeneity and prognosis of single organ metastases in gastric cancer.Translational gastroenterology and hepatology · 2024
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Epidemiological and pathological characteristics of spinal metastases from gastrointestinal cancers - a series of 40 cases.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Angelica PetrilloMedical Oncology Unit, Ospedale del Mare, 80147 Naples, Italy.ORCID 0000-0001-5489-5733
Emilio Francesco GiuntaMedical Oncology Unit, Ospedale del Mare, 80147 Naples, Italy.ORCID 0000-0002-5383-4469
Annalisa PappalardoMedical Oncology Unit, Ospedale del Mare, 80147 Naples, Italy.
Davide BossoMedical Oncology Unit, Ospedale del Mare, 80147 Naples, Italy.
Laura AttademoMedical Oncology Unit, Ospedale del Mare, 80147 Naples, Italy.
Cinzia CardalesiMedical Oncology Unit, Ospedale del Mare, 80147 Naples, Italy.
Anna DianaMedical Oncology Unit, Ospedale del Mare, 80147 Naples, Italy.ORCID 0000-0003-1131-8690
Antonietta FabbrociniMedical Oncology Unit, Ospedale del Mare, 80147 Naples, Italy.
Teresa FabozziMedical Oncology Unit, Ospedale del Mare, 80147 Naples, Italy.
Pasqualina GiordanoMedical Oncology Unit, Ospedale del Mare, 80147 Naples, Italy.
Margaret OttavianoMedical Oncology Unit, Ospedale del Mare, 80147 Naples, Italy.ORCID 0000-0001-9589-0808
Mario RosanovaMedical Oncology Unit, Ospedale del Mare, 80147 Naples, Italy.
Antonia SilvestriMedical Oncology Unit, Ospedale del Mare, 80147 Naples, Italy.
Piera FedericoMedical Oncology Unit, Ospedale del Mare, 80147 Naples, Italy.ORCID 0000-0002-0863-7546
Bruno DanieleMedical Oncology Unit, Ospedale del Mare, 80147 Naples, Italy.ORCID 0000-0002-2638-3156
University of Campania "Luigi Vanvitelli" · ITRegione Campania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC) is the third cause of cancer-related death worldwide; the prognosis is poor especially in the case of metastatic disease. Liver, lymph nodes, peritoneum, and lung are the most frequent sites of metastases from GC; however, bone metastases from GC have been reported in the literature. Nevertheless, it is unclear how the metastatic sites may affect the prognosis. In particular, knowledge about the impact of bone metastases on GC patients' outcome is scant, and this may be related to the rarity of bone lesions and/or their underestimation at the time of diagnosis. In fact, there is still a lack of specific recommendation for their detection at the diagnosis. Then, the majority of the evidences in this field came from retrospective analysis on very heterogeneous study populations. In this context, the aim of this narrative review is to delineate an overview about the evidences existing about bone metastases in GC patients, focusing on their incidence and biology, the prognostic role of bone involvement, and their possible implication in the treatment choice.

Indexed as

bone flaremetastatic gastric cancerRANK-Lstage IVtarget therapytreatment

Identifiers

PMID33921760
PMCPMC8073984
OpenAlexW3154016454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.