ArticleChildren (Basel, Switzerland)2021
Validity of Appendicitis Inflammatory Response Score in Distinguishing Perforated from Non-Perforated Appendicitis in Children.
Article in Children (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 4 of them syntheses that pooled it.
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Who cites it
47 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Diagnostic Accuracy of Non-Contrast CT for Acute Appendicitis in the Emergency Department: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Diagnostic Accuracy of Non-Radiologist-Performed Ultrasound for Diagnosing Acute Appendicitis in Pediatric Patients: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Swedish national guidelines for diagnosis and management of acute appendicitis in adults and children.BJS open · 2025Guideline
- Hyponatremia as a predictor of complicated appendicitis: a systematic review and meta-analysis.Biomarkers in medicine · 2024Pooled it
- Comparison of the Alvarado Score with Alternative Diagnostic Tools in Pediatric Acute Appendicitis: A Literature Review.Pediatric reports · 2026Review
- Analysis of diagnostic efficacy of serum miR-126-5p levels for stratifying severity in pediatric acute appendicitis.BMC pediatrics · 2026Article
- Appendicitis inflammatory response versus pediatric appendicitis score for grading disease severity in children.Scientific reports · 2026Observational
- Impact of Trocar Position on Surgical Site Infection After Pediatric Laparoscopic Appendectomy: A 15-Year Single-Center Study.Medical sciences (Basel, Switzerland) · 2026Article
- The Role of Emerging Immune-Inflammatory Indexes in the Preoperative Differentiation of Complicated and Uncomplicated Acute Appendicitis: A Single-Center Retrospective Analysis.Diagnostics (Basel, Switzerland) · 2025Article
- Artificial intelligence in acute appendicitis: A comprehensive review of machine learning and deep learning applications.World journal of gastroenterology · 2025Review
- Neutrophil-to-lymphocyte ratio as an adjunct to clinical scoring systems for diagnosing perforated appendicitis in children: prospective cohort study.Annals of medicine and surgery (2012) · 2025Article
- Salivary C-Reactive Protein: A Non-Invasive Alternative to Serum CRP in Pediatric Acute Appendicitis.Molecules (Basel, Switzerland) · 2025Article
- The Safety and Feasibility of Single-Stage Versus Staged Laparoscopic Approach for Acute Appendicitis with Inguinal Hernia in Pediatric Patients: A Comparative Study.Journal of clinical medicine · 2025Article
- Acute Appendicitis or Appendiceal Diverticulitis? A Case Report and Systematic Literature Review.Clinics and practice · 2025Review
- PAN-Immune inflammation value: a new biomarker for diagnosing appendicitis in children??BMC pediatrics · 2025Article
- Surgical site infection following appendectomy in children.Scientific reports · 2025Article
- Diagnostic value of the MZXBTCH scoring system for acute complex appendicitis.Scientific reports · 2025Article
- Predictive Factors of Acute Appendicitis and Its Outcomes Among the Pediatric Age Group.Cureus · 2025Article
- The Role of Vascular Cell Adhesion Molecule-1 (VCAM-1) in Predicting Complicated Appendicitis in Children.Diagnostics (Basel, Switzerland) · 2024Article
- Applying an explainable machine learning model might reduce the number of negative appendectomies in pediatric patients with a high probability of acute appendicitis.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis prospective observational study aimed to evaluate the validity of appendicitis inflammatory response (AIR) score in differentiating advanced (perforated) from simple (non-perforated) appendicitis in pediatric patients.
methodsA single-center prospective cross-sectional study was conducted between 1 January 2019 until 1 May 2020 including 184 pediatric patients who underwent appendectomy. Based on the intraoperative finding of advanced (
resultsThe median value of the AIR score in the perforated and non-perforated groups was 10 (interquartile range, IQR 9, 11), and was 7 (IQR 6, 9), respectively (
conclusionsAcute appendicitis can be detected with a high level of sensitivity and specificity using the AIR score. Also, the AIR score may differentiate perforated from non-perforated appendicitis in pediatric patients with a high level of accuracy.
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