Evidence map›Paper›PMID 33921307›Full record

ArticlePolymers2021

Fabrication of Poly(Ethylene-glycol 1,4-Cyclohexane Dimethylene-Isosorbide-Terephthalate) Electrospun Nanofiber Mats for Potential Infiltration of Fibroblast Cells.

Sofia El-Ghazali, Muzamil Khatri, Mujahid Mehdi, Davood Kharaghani, Yasushi Tamada, Anna Katagiri, Shunichi Kobayashi, Ick Soo Kim

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Sofia El-GhazaliDepartment of Biomedical Engineering, Division of Biomedical Engineering, Faculty of Science and Technology, Shinshu University, Tokida 3-15-1, Ueda, Nagano Prefecture 386-8567, Japan.
Muzamil KhatriNano Fusion Technology Research Group, Division of Frontier Fibers, Institute for Fiber Engineering (IFES), Interdisciplinary Cluster for Cutting Edge Research (ICCER), Shinshu University, Tokida 3-15-1, Ueda, Nagano Prefecture 386-8567, Japan.
Mujahid MehdiNational Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Suzhou 215123, China.ORCID 0000-0002-4564-303X
Davood KharaghaniDepartment of Calcified Tissue Biology, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-Ku, Hiroshima 734-8553, Japan.
Yasushi TamadaFaculty of Textile Science and Technology Bioresource and Environmental Science, Shinshu University, Tokida 3-15-1, Ueda, Nagano Prefecture 386-8567, Japan.
Anna KatagiriFaculty of Textile Science and Technology Bioresource and Environmental Science, Shinshu University, Tokida 3-15-1, Ueda, Nagano Prefecture 386-8567, Japan.
Shunichi KobayashiDepartment of Biomedical Engineering, Division of Biomedical Engineering, Faculty of Science and Technology, Shinshu University, Tokida 3-15-1, Ueda, Nagano Prefecture 386-8567, Japan.
Ick Soo KimNano Fusion Technology Research Group, Division of Frontier Fibers, Institute for Fiber Engineering (IFES), Interdisciplinary Cluster for Cutting Edge Research (ICCER), Shinshu University, Tokida 3-15-1, Ueda, Nagano Prefecture 386-8567, Japan.ORCID 0000-0003-2244-4369
Shinshu University · JPHiroshima University · JPSoochow University · CN

Funding

Shinshu University Advanced Leading Graduate Program by the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan. N/A
6 · The paper itself

Abstract

Recently, bio-based electrospun nanofiber mats (ENMs) have gained substantial attention for preparing polymer-based biomaterials intended for use in cell culture. Herein, we prepared poly(ethylene-glycol 1,4-Cyclohexane dimethylene-isosorbide-terephthalate) (PEICT) ENMs using the electrospinning technique. Cell adhesion and cell viability of PEICT ENMs were checked by fibroblast cell culture. Field emission electron microscope (FE-SEM) image showed a randomly interconnected fiber network, smooth morphology, and cell adhesion on PEICT ENM. Fibroblasts were cultured in an adopted cell culturing environment on the surface of PEICT ENMs to confirm their biocompatibility and cell viability. Additionally, the chemical structure of PEICT ENM was checked under Fourier-transform infrared (FTIR) spectroscopy and the results were supported by -ray photoelectron (XPS) spectroscopy. The water contact angle (WCA) test showed the hydrophobic behavior of PEICT ENMs in parallel to good fibroblast cell adhesion. Hence, the results confirmed that PEICT ENMs can be potentially utilized as a biomaterial.

Indexed as

biobased polyestercell adhesioncell culturecell viabilityfibroblastnanofibers

Identifiers

PMID33921307
PMCPMC8069266
OpenAlexW3154991948

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.