ReviewPharmaceutics2021
Topical Antiseptic Formulations for Skin and Soft Tissue Infections.
Review in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Antibiotic Nanoparticles-Loaded Wound Dressings AgainstInternational journal of nanomedicine · 2024Pooled it
- Design and Optimization of Self-Nanoemulsifying Drug Delivery Systems to Enhance the Anti-Inflammatory Efficacy ofPharmaceutics · 2026Article
- Epidermicin NI01 demonstrates potentJAC-antimicrobial resistance · 2026Article
- Zinc oxide nanoparticles restore susceptibility to chlorhexidine and benzalkonium chloride in methicillin-resistant Staphylococcus aureus isolated from burn infections.Wiener medizinische Wochenschrift (1946) · 2026Article
- Controlling Staphylococcus aureus skin infections by targeting biofilm and virulence properties using FDA-approved antiseptics and skin care products.Folia microbiologica · 2026Article
- Surgical site infection prevention: a scoping review of strategies, implementation barriers, and emerging approaches.Frontiers in public health · 2026Article
- Evaluation of the Preoperative Antiseptic Efficacy of Ozone on Dog Skin in Comparison with Traditional Methods.Veterinary sciences · 2025Article
- Antibacterial Creams Containing Cationic Carbosilane Dendrimers for Wound Treatment.ACS applied polymer materials · 2025Article
- A review of advancements in antiseptics for wound care in diabetic and non-diabetic patients.Journal of diabetes and metabolic disorders · 2025Review
- Antimicrobial activity of tea tree and lavender essential oils and their effects on hatching performance and eggshell bacterial count of Japanese quail eggs.BMC veterinary research · 2025Article
- Advance Screening of Bis-azetidinone Derivatives: Synthesis, Spectroscopy, Antioxidant and Antimicrobial Analysis with Molecular Docking Assessment.Current organic synthesis · 2025Article
- Generalized Dermatitis Caused byCase reports in veterinary medicine · 2025Article
- Spread of livestock-associated methicillin-resistantOpen veterinary journal · 2024Review
- Article
- A Comparative Study of the Chemical Properties and Antibacterial Activity of Four Different Ozonated Oils for Veterinary Purposes.Veterinary sciences · 2024Article
- Antibiotics againstPharmaceutics · 2024Article
- Cell migration, DNA fragmentation and antibacterial properties of novel silver doped calcium polyphosphate nanoparticles.Scientific reports · 2024Article
- Effect of Addition of Cetylpyridinium Chloride Cationic Surfactant on the Antimicrobial Activity of Chlorhexidine Endodontic Irrigant.International journal of dentistry · 2024Article
- Polyphenols: Natural Preservatives with Promising Applications in Food, Cosmetics and Pharma Industries; Problems and Toxicity Associated with Synthetic Preservatives; Impact of Misleading Advertisements; Recent Trends in Preservation and Legislation.Materials (Basel, Switzerland) · 2023Review
- Nanomaterials Based on Honey and Propolis for Wound Healing-A Mini-Review.Nanomaterials (Basel, Switzerland) · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Skin and soft tissue infections (SSTIs) are usually acute conditions of inflammatory microbial occupation of the skin layers and underlying soft tissues. SSTIs are one of the most frequent types of infection, typically requiring medical intervention and contribute to morbidity and mortality in both primary care and hospitalised patients. Due to the dramatic rise of antibiotic resistance, antiseptic agents can be potential alternatives for the prevention and treatment of SSTIs. Notably, they are commonly recommended in many global practical guidelines for use in per- and post- operative procedures. A range of antiseptics, including chlorhexidine, triclosan, alcohol, and povidone-iodine, are used and are mainly formulated as traditional, simple dosage forms such as solutions and semi-solids. However, in recent years, there have been studies reporting the potential for nanotechnology in the delivery of antiseptics. In this review, we have collated the scientific literature that focuses on topical antiseptic formulations for prevention and treatment of SSTIs, and have divided findings into traditional and advanced formulations. We conclude that although nanotechnological formulations have demonstrated potential advantages for delivering drugs; nevertheless, there is still scope for traditional formulations and further development of optimised topical formulations to address the rise of antimicrobial resistance.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.