ReviewAnimals : an open access journal from MDPI2021
Adverse Effects of Heat Stress on the Intestinal Integrity and Function of Pigs and the Mitigation Capacity of Dietary Antioxidants: A Review.
Review in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 51 citations in OpenAlex.
- Growth Performance and Antioxidant Responses to Dietary Flavonoids in Swine: A Systematic Review and Meta-Analysis with Exploratory Dose-Time Relationships.Antioxidants (Basel, Switzerland) · 2026Review
- High-protein diets improve growth, carcass traits, and intestinal morphology of local rabbits under chronic heat stress.Tropical animal health and production · 2026Article
- Nicotinamide Riboside Supplementation Protects Against Heat-Induced Skeletal Muscle Injury in Female Mice.Muscles (Basel, Switzerland) · 2026Article
- Integrative multi-omics analysis reveals systemic and intestinal responses to heat stress in finishing pigs.Journal of animal science and technology · 2026Article
- Benefits of Utilization of Hydroxy-Methionine in Diets of Finishing Pigs Raised Under Hot Environmental Conditions.Veterinary sciences · 2026Article
- Investigating alterations associated with heat stress and the recovery of the intestinal barrier using IPEC-J2 as an intestinal epithelial porcine cell model.Scientific reports · 2026Article
- Seasonal dynamics and nutritional risk factors of gastric ulcers in fattening pigs: Results from a one-year field study in Slovakia.Veterinarni medicina · 2025Article
- Breed- and Line-Dependent Severity of Inflammation and Necrosis Syndrome in AI Boars, and the Related Risk of Inflammation and Necrosis in Their Progeny.Veterinary sciences · 2025Article
- Inflammation and Necrosis Syndrome in Young Piglets-A Longitudinal Study.Veterinary sciences · 2025Article
- Grape Pomace and Ferulic Acid Improve Antioxidant Enzyme Activity and Gut Histomorphometry in Heat-Stressed Finishing Pigs.Animals : an open access journal from MDPI · 2025Article
- Distribution of perfluorooctanoic acid in exposed female postpubertal pigs in thermal neutral or heat-stressed conditions.Toxicological sciences : an official journal of the Society of Toxicology · 2025Article
- Effect of heat stress on pig production and its mitigation strategies: a review.Tropical animal health and production · 2025Review
- Screening of Piglets for Signs of Inflammation and Necrosis as Early Life Indicators of Animal Health and Welfare Hazards.Animals : an open access journal from MDPI · 2025Article
- Intestinal Barrier Damage and Growth Retardation Caused by Exposure to Polystyrene Nanoplastics Through Lactation Milk in Developing Mice.Nanomaterials (Basel, Switzerland) · 2025Article
- Effects of dietaryFrontiers in microbiology · 2025Article
- How to assess antioxidant activity? Advances, limitations, and applications of in vitro, in vivo, and ex vivo approaches.Food production, processing and nutrition · 2025Review
- Effects of dietary canthaxanthin on egg production, serum parameters, and intestinal health in indigenous chickens under heat stress.Frontiers in veterinary science · 2025Article
- Heat Stress Induces Alterations in Gene Expression of Actin Cytoskeleton and Filament of Cellular Components Causing Gut Disruption in Growing-Finishing Pigs.Animals : an open access journal from MDPI · 2024Article
- The Effects of Zinc Oxide Nanoparticles on Antioxidation, Inflammation, Tight Junction Integrity, and Apoptosis in Heat-Stressed Bovine Intestinal Epithelial Cells In Vitro.Biological trace element research · 2024Article
- Therapeutic effects of mitoquinol during an acute heat stress challenge in growing gilts.Journal of animal science · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heat stress (HS) significantly affects the performance of pigs by its induced stressors such as inflammation, hypoxia and oxidative stress (OS), which mightily strain the intestinal integrity and function of pigs. As heat stress progresses, several mechanisms in the intestinal epithelium involved in the absorption of nutrients and its protective functions are altered. Changes in these mechanisms are mainly driven by cellular oxidative stress, which promotes disruption of intestinal homeostasis, leading to intestinal permeability, emphasizing intestinal histology and morphology with little possibility of recovering even after exposure to HS. Identification and understanding of these altered mechanisms are crucial for providing appropriate intervention strategies. Therefore, it is this papers' objective to review the important components for intestinal integrity that are negatively affected by HS and its induced stressors. With due consideration to the amelioration of such effects through nutritional intervention, this work will also look into the capability of dietary antioxidants in mitigating such adverse effects and maintaining the intestine's integrity and function upon the pigs' exposure to high environmental temperature.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.