Evidence map›Paper›PMID 33920899›Full record

ArticleJournal of clinical medicine2021

The Relationship between Hospital Volume and In-Hospital Mortality of Severely Injured Patients in Dutch Level-1 Trauma Centers.

Charlie A Sewalt, Esmee Venema, Erik van Zwet, Jan C van Ditshuizen, Stephanie C E Schuit, Suzanne Polinder, Hester F Lingsma, Dennis den Hartog, On Behalf Of Ltr Research Group

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Transport and destination hospital for patients with suspected multiple and/or severe injuries - a systematic review and clinical practice guideline update.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Pooled it
  2. Article
  3. Article
  4. Funnel plots a graphical instrument for the evaluation of population performance and quality of trauma care: a blueprint of implementation.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2023
    Observational
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Charlie A SewaltDepartment of Public Health, Erasmus MC Medical Center, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0003-3270-4814
Esmee VenemaDepartment of Public Health, Erasmus MC Medical Center, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0003-1631-6635
Erik van ZwetDepartment of Biostatistics, Leiden University Medical Center, 2333 ZA Leiden, The Netherlands.
Jan C van DitshuizenTrauma Center South West Netherlands, Erasmus MC Medical Center, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0003-0765-0092
Stephanie C E SchuitDepartment of Internal Medicine, Erasmus MC Medical Center, 3015 GD Rotterdam, The Netherlands.
Suzanne PolinderDepartment of Public Health, Erasmus MC Medical Center, 3015 GD Rotterdam, The Netherlands.
Hester F LingsmaDepartment of Public Health, Erasmus MC Medical Center, 3015 GD Rotterdam, The Netherlands.
Dennis den HartogTrauma Center South West Netherlands, Erasmus MC Medical Center, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0002-4531-6098
On Behalf Of Ltr Research Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Centralization of trauma centers leads to a higher hospital volume of severely injured patients (Injury Severity Score (ISS) > 15), but the effect of volume on outcome remains unclear. The aim of this study was to determine the association between hospital volume of severely injured patients and in-hospital mortality in Dutch Level-1 trauma centers. A retrospective observational cohort study was performed using the Dutch trauma registry. All severely injured adults (ISS > 15) admitted to a Level-1 trauma center between 2015 and 2018 were included. The effect of hospital volume on in-hospital mortality was analyzed with random effects logistic regression models with a random intercept for Level-1 trauma center, adjusted for important demographic and injury characteristics. A total of 11,917 severely injured patients from 13 Dutch Level-1 trauma centers was included in this study. Hospital volume varied from 120 to 410 severely injured patients per year. Observed mortality rates varied between 12% and 24% per center. After case-mix correction, no statistically significant differences between low- and high-volume centers were demonstrated (adjusted odds ratio 0.97 per 50 extra patients per year, 95% Confidence Interval 0.90-1.04,

Indexed as

centralizationmajor traumavolume-outcome relationship

Identifiers

PMID33920899
PMCPMC8071237

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.