Evidence map›Paper›PMID 33920895›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Computational Design and Development of Benzodioxane-Benzamides as Potent Inhibitors of FtsZ by Exploring the Hydrophobic Subpocket.

Valentina Straniero, Victor Sebastián-Pérez, Lorenzo Suigo, William Margolin, Andrea Casiraghi, Martina Hrast, Carlo Zanotto, Irena Zdovc, Antonia Radaelli, Ermanno Valoti

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Valentina StranieroDipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Luigi Mangiagalli, 25, 20133 Milano, Italy.ORCID 0000-0002-5089-0879
Victor Sebastián-PérezCentro de Investigaciones Biológicas (CSIC), Ramiro de Maeztu 9, 28040 Madrid, Spain.
Lorenzo SuigoDipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Luigi Mangiagalli, 25, 20133 Milano, Italy.ORCID 0000-0002-8958-1547
William MargolinDepartment of Microbiology and Molecular Genetics, McGovern Medical School, University of Texas, Houston, TX 77030, USA.ORCID 0000-0001-6557-7706
Andrea CasiraghiDipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Luigi Mangiagalli, 25, 20133 Milano, Italy.
Martina HrastFaculty of Pharmacy, University of Ljubljana, Aškerčeva cesta, 7, 1000 Ljubljana, Slovenia.ORCID 0000-0003-0488-2445
Carlo ZanottoDipartimento di Biotecnologie Mediche e Medicina Traslazionale, Università degli Studi di Milano, Via Vanvitelli, 32, 20129 Milano, Italy.
Irena ZdovcVeterinary Faculty, University of Ljubljana, Gerbičeva, 60, 1000 Ljubljana, Slovenia.
Antonia RadaelliDipartimento di Biotecnologie Mediche e Medicina Traslazionale, Università degli Studi di Milano, Via Vanvitelli, 32, 20129 Milano, Italy.
Ermanno ValotiDipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Luigi Mangiagalli, 25, 20133 Milano, Italy.ORCID 0000-0002-5608-3875
University of Milan · ITUniversity of Ljubljana · SICentro de Investigaciones Biológicas Margarita Salas · ES

Funding

Mechanisms and Regulation of Cell Division in BacteriaR35GM131705 · NIGMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WILLIAM MARGOLIN · 2019 to 2026
$3.8M
NIGMS NIH HHS R35 GM131705NIH HHS GM131705
6 · The paper itself

Abstract

Multidrug resistant

Indexed as

antibiotic-resistanceBacillus subtilisFtsZFtsZ inhibitiongram positive-dependent diseasesMICMRSAMSSAZ ring

Identifiers

PMID33920895
PMCPMC8071314
OpenAlexW3153782946

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.