Evidence map›Paper›PMID 33920841›Full record

ArticleMolecules (Basel, Switzerland)2021

Ursolic Acid Lactone Obtained from

Norman Balcazar, Laura I Betancur, Diana L Muñoz, Frankly J Cabrera, Adriana Castaño, Luis F Echeverri, Sergio Acin

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Review
  3. A triterpene-enriched natural extract fromPharmaceutical biology · 2025
    Article
  4. Advances in pharmacological and pharmaceutical sciences · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Norman BalcazarGENMOL Group, Sede de Investigación Universitaria, University of Antioquia, Medellín 050010, Antioquia, Colombia.ORCID 0000-0002-1860-1176
Laura I BetancurGENMOL Group, Sede de Investigación Universitaria, University of Antioquia, Medellín 050010, Antioquia, Colombia.ORCID 0000-0001-6062-6775
Diana L MuñozDepartment of Physiology and Biochemistry, Faculty of Medicine, University of Antioquia, Medellín 050010, Antioquia, Colombia.
Frankly J CabreraGENMOL Group, Sede de Investigación Universitaria, University of Antioquia, Medellín 050010, Antioquia, Colombia.
Adriana CastañoQOPN Group, Faculty of Exact and Natural Sciences, Sede de Investigación Universitaria, University of Antioquia, Medellín 050010, Antioquia, Colombia.
Luis F EcheverriQOPN Group, Faculty of Exact and Natural Sciences, Sede de Investigación Universitaria, University of Antioquia, Medellín 050010, Antioquia, Colombia.ORCID 0000-0002-9530-8395
Sergio AcinGENMOL Group, Sede de Investigación Universitaria, University of Antioquia, Medellín 050010, Antioquia, Colombia.ORCID 0000-0001-7335-2865
Universidad de Antioquia · CO

Funding

Departamento Administrativo de Ciencia, Tecnología e Innovación (COLCIENCIAS) 111577756880
6 · The paper itself

Abstract

Obesity has a strong relationship to insulin resistance and diabetes mellitus, a chronic metabolic disease that alters many physiological functions. Naturally derived drugs have aroused great interest in treating obesity, and triterpenoids are natural compounds with multiple biological activities and antidiabetic mechanisms. Here, we evaluated the bioactivity of ursolic acid lactone (UAL), a lesser-known triterpenoid, obtained from

Indexed as

3T3-L1 CellsAdipocytesAnimalsEucalyptusHepatocytesLactonesMacrophagesMiceMuscle CellsPhosphorylationTriglyceridesTriterpenesUrsolic AcidLactonesTriglyceridesTriterpenesUrsolic Acidadipocytesdiabeteshepatocytesmacrophagesmyocytesursolic acid lactone

Identifiers

PMID33920841
PMCPMC8071196
OpenAlexW3153418511

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.