Evidence map›Paper›PMID 33920761›Full record

ArticleInternational journal of environmental research and public health2021

Pro-Apoptotic Activity of Artichoke Leaf Extracts in Human HT-29 and RKO Colon Cancer Cells.

Milena Villarini, Mattia Acito, Raffaella di Vito, Samuele Vannini, Luca Dominici, Cristina Fatigoni, Rita Pagiotti, Massimo Moretti

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Sustainable Extraction ofInternational journal of molecular sciences · 2026
    Article
  3. A Phytochemical and Biological Characterization ofMolecules (Basel, Switzerland) · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Olive Mill Wastewater Extract: In Vitro Genotoxicity/Antigenotoxicity Assessment on HepaRG Cells.International journal of environmental research and public health · 2024
    Article
  9. Review
  10. Plants (Basel, Switzerland) · 2024
    Article
  11. Review
  12. Investigating the Medicinal Potential ofAdvances in pharmacological and pharmaceutical sciences · 2024
    Article
  13. Red Kale (Molecules (Basel, Switzerland) · 2023
    Article
  14. Article
  15. Article
  16. Interdisciplinary Approach to Improve Agri-Food Safety and Quality.International journal of environmental research and public health · 2022
    Article
  17. The Employment of GeneraNutrients · 2022
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Milena VillariniUnit of Public Health, Department of Pharmaceutical Sciences, University of Perugia, via del Giochetto, 06122 Perugia, Italy.ORCID 0000-0002-8769-883X
Mattia AcitoUnit of Public Health, Department of Pharmaceutical Sciences, University of Perugia, via del Giochetto, 06122 Perugia, Italy.ORCID 0000-0003-1808-1999
Raffaella di VitoUnit of Public Health, Department of Pharmaceutical Sciences, University of Perugia, via del Giochetto, 06122 Perugia, Italy.ORCID 0000-0003-1661-3517
Samuele VanniniUnit of Public Health, Department of Pharmaceutical Sciences, University of Perugia, via del Giochetto, 06122 Perugia, Italy.
Luca DominiciUnit of Public Health, Department of Pharmaceutical Sciences, University of Perugia, via del Giochetto, 06122 Perugia, Italy.
Cristina FatigoniUnit of Public Health, Department of Pharmaceutical Sciences, University of Perugia, via del Giochetto, 06122 Perugia, Italy.ORCID 0000-0002-7495-8671
Rita PagiottiUnit of Plant Biology, Department of Pharmaceutical Sciences, University of Perugia, via del Giochetto, 06122 Perugia, Italy.
Massimo MorettiUnit of Public Health, Department of Pharmaceutical Sciences, University of Perugia, via del Giochetto, 06122 Perugia, Italy.ORCID 0000-0002-5038-8619
University of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background:

Indexed as

Colonic NeoplasmsCynara scolymusAntioxidantsHT29 CellsHumansPlant ExtractsAntioxidantsPlant Extractsantitumour activityapoptosisartichokecell proliferationcomet assayCynara scolymusHT-29 and RKO tumour cells

Identifiers

PMID33920761
PMCPMC8071198
OpenAlexW3155707693

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.