Evidence map›Paper›PMID 33920725›Full record

Trial reportNutrients2021

Dietary Supplementation with Selenium and Coenzyme Q

Urban Alehagen, Jan Aaseth, Tomas L Lindahl, Anders Larsson, Jan Alexander

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Study on the molecular aspect of cardioprotective effects of selenium: a mini-review.Journal of basic and clinical physiology and pharmacology · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Relationship between selenium status, selenoproteins and COVID-19 and other inflammatory diseases: A critical review.Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) · 2023
    Review
  12. Review
  13. The Role of Selenium in Pathologies: An Updated Review.Antioxidants (Basel, Switzerland) · 2022
    Review
  14. Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Urban AlehagenDivision of Cardiovascular Medicine, Department of Health, Medicine and Caring Sciences, Linköping University, SE-581 85 Linköping, Sweden.
Jan AasethResearch Department, Innlandet Hospital Trust, N-2381 Brumunddal, Norway.ORCID 0000-0002-7518-5703
Tomas L LindahlDivision of Clinical Chemistry and Pharmacology, Department of Biomedical and Clinical Sciences, Linköping University, SE-581 85 Linköping, Sweden.ORCID 0000-0003-0174-8152
Anders LarssonDepartment of Medical Sciences, Uppsala University, SE-751 85 Uppsala, Sweden.ORCID 0000-0003-3161-0402
Jan AlexanderNorwegian Institute of Public Health, N-0403 Oslo, Norway.ORCID 0000-0002-6381-5720
Linköping University · SEInnlandet Hospital Trust · NONorwegian Institute of Public Health · NOUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A low intake of selenium is associated with increased cardiovascular mortality. This could be reduced by supplementation with selenium and coenzyme Q

Indexed as

Dietary SupplementsAgedAged, 80 and overBiomarkersCardiovascular DiseasesDouble-Blind MethodFemaleFibrin Fibrinogen Degradation ProductsHumansMaleMyocardial IschemiaSeleniumSwedenUbiquinoneBiomarkerscoenzyme Q10Fibrin Fibrinogen Degradation Productsfibrin fragment DSeleniumUbiquinonecardiovascular mortalitycoenzyme Q10D-dimerelderlyinterventionselenium

Identifiers

PMID33920725
PMCPMC8073286
OpenAlexW3154029357

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.