Evidence map›Paper›PMID 33920691›Full record

ArticleJournal of personalized medicine2021

Autonomic Dysfunction Contributes to Impairment of Cerebral Autoregulation in Patients with Epilepsy.

Shu-Fang Chen, Hsiu-Yung Pan, Chi-Ren Huang, Jyun-Bin Huang, Teng-Yeow Tan, Nai-Ching Chen, Chung-Yao Hsu, Yao-Chung Chuang

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Shu-Fang ChenDepartment of Neurology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 83301, Taiwan.
Hsiu-Yung PanDepartment of Neurology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 83301, Taiwan.
Chi-Ren HuangDepartment of Neurology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 83301, Taiwan.
Jyun-Bin HuangDepartment of Neurology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 83301, Taiwan.
Teng-Yeow TanDepartment of Neurology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 83301, Taiwan.
Nai-Ching ChenDepartment of Neurology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 83301, Taiwan.ORCID 0000-0003-2684-0377
Chung-Yao HsuDepartment of Neurology, School of Medicine, College of Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Yao-Chung ChuangDepartment of Neurology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung 83301, Taiwan.
Chang Gung University · TWKaohsiung Chang Gung Memorial Hospital · TWKaohsiung Medical University · TWNational Sun Yat-sen University · TW

Funding

Chang Gung Medical Foundation CMRPG8I0041
6 · The paper itself

Abstract

Patients with epilepsy frequently experience autonomic dysfunction and impaired cerebral autoregulation. The present study investigates autonomic function and cerebral autoregulation in patients with epilepsy to determine whether these factors contribute to impaired autoregulation. A total of 81 patients with epilepsy and 45 healthy controls were evaluated, assessing their sudomotor, cardiovagal, and adrenergic functions using a battery of autonomic nervous system (ANS) function tests, including the deep breathing, Valsalva maneuver, head-up tilting, and Q-sweat tests. Cerebral autoregulation was measured by transcranial Doppler examination during the breath-holding test, the Valsalva maneuver, and the head-up tilting test. Autonomic functions were impaired during the interictal period in patients with epilepsy compared to healthy controls. The three indices of cerebral autoregulation-the breath-holding index (BHI), an autoregulation index calculated in phase II of the Valsalva maneuver (ASI), and cerebrovascular resistance measured in the second minute during the head-up tilting test (CVR

Indexed as

autonomic nervous system dysfunctioncerebral autoregulationsuddentemporal lobe epilepsyunexplained death in epilepsyvascular risk

Identifiers

PMID33920691
PMCPMC8073240
OpenAlexW3154195943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.