Evidence map›Paper›PMID 33920678›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

High-Efficacy α,β-Dehydromonacolin S Improves Hepatic Steatosis and Suppresses Gluconeogenesis Pathway in High-Fat Diet-Induced Obese Rats.

Jutatip Kaewmalee, Atcharaporn Ontawong, Acharaporn Duangjai, Chittreeya Tansakul, Vatcharin Rukachaisirikul, Chatchai Muanprasat, Chutima Srimaroeng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Modulatory Effects ofNutrients · 2026
    Article
  2. Article
  3. Holy Basil (Plants (Basel, Switzerland) · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jutatip KaewmaleeDepartment of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.
Atcharaporn OntawongDivision of Physiology, School of Medical Sciences, University of Phayao, Phayao 56000, Thailand.
Acharaporn DuangjaiDivision of Physiology, School of Medical Sciences, University of Phayao, Phayao 56000, Thailand.
Chittreeya TansakulDivision of Physical Science and Center of Excellence for Innovation in Chemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand.ORCID 0000-0003-3002-7215
Vatcharin RukachaisirikulDivision of Physical Science and Center of Excellence for Innovation in Chemistry, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla 90112, Thailand.
Chatchai MuanprasatChakri Naruebodindra Medical Institute, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Samutprakarn 10540, Thailand.
Chutima SrimaroengDepartment of Physiology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.ORCID 0000-0002-5537-1023
Chiang Mai University · THPrince of Songkla University · THUniversity of Phayao · THMahidol University · TH

Funding

NSTDA Chair Professor grant of the Crown Property Bureau and the National Science and Technology Development Agency 4Thailand Research Fund RSA5980009
6 · The paper itself

Abstract

Isolated α,β-dehydromonacolin S (

Indexed as

3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitorgluconeogenesishepatic steatosislovastatin analogstatintype 2 diabetes mellitusα,β-dehydromonacolin S

Identifiers

PMID33920678
PMCPMC8073358
OpenAlexW3153617239

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.