Evidence map›Paper›PMID 33920598›Full record

ArticleViruses2021

Genetic Characterization of a Neurovirulent West Nile Virus Variant Associated with a Fatal Great Grey Owl Infection.

Katarína Peňazziová, Ľuboš Korytár, Patrik Pastorek, Juraj Pistl, Diana Rusňáková, Tomáš Szemes, Viktória Čabanová, Martina Ličková, Kristína Boršová, Boris Klempa and 1 more

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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  4. Surveillance ofHeliyon · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Katarína PeňazziováDepartment of Microbiology and Immunology, University of Veterinary Medicine and Pharmacy in Košice, Komenského 73, 04181 Košice, Slovakia.ORCID 0000-0002-3434-5977
Ľuboš KorytárDepartment of Epizootiology, Parasitology and Protection of One Health, University of Veterinary Medicine and Pharmacy in Košice, Komenského 73, 04181 Košice, Slovakia.ORCID 0000-0002-8559-3559
Patrik PastorekZOO Košice, Ulica k Zoologickej Záhrade 1, 04001 Košice, Slovakia.
Juraj PistlDepartment of Microbiology and Immunology, University of Veterinary Medicine and Pharmacy in Košice, Komenského 73, 04181 Košice, Slovakia.
Diana RusňákováDepartment of Molecular Biology, Faculty of Natural Sciences and Science Park, Comenius University in Bratislava, Ilkovičova 8, 84104 Bratislava, Slovakia.
Tomáš SzemesDepartment of Molecular Biology, Faculty of Natural Sciences and Science Park, Comenius University in Bratislava, Ilkovičova 8, 84104 Bratislava, Slovakia.
Viktória ČabanováBiomedical Research Center of Slovak Academy of Sciences, Department of Virus Ecology, Institute of Virology, Dúbravská Cesta 9, 84505 Bratislava, Slovakia.ORCID 0000-0001-8725-9362
Martina LičkováBiomedical Research Center of Slovak Academy of Sciences, Department of Virus Ecology, Institute of Virology, Dúbravská Cesta 9, 84505 Bratislava, Slovakia.ORCID 0000-0001-5357-6618
Kristína BoršováBiomedical Research Center of Slovak Academy of Sciences, Department of Virus Ecology, Institute of Virology, Dúbravská Cesta 9, 84505 Bratislava, Slovakia.ORCID 0000-0002-1086-3219
Boris KlempaBiomedical Research Center of Slovak Academy of Sciences, Department of Virus Ecology, Institute of Virology, Dúbravská Cesta 9, 84505 Bratislava, Slovakia.ORCID 0000-0002-6931-1224
Tomáš CsankDepartment of Microbiology and Immunology, University of Veterinary Medicine and Pharmacy in Košice, Komenského 73, 04181 Košice, Slovakia.ORCID 0000-0003-2055-9293
Biomedical Research Center of the Slovak Academy of Sciences · SKUniversity of Veterinary Medicine in Košice · SKComenius University Bratislava · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study reports on a fatal case of a captive great grey owl infected with the West Nile virus (WNV) in the zoological garden Košice, eastern Slovakia (Central Europe). The tissue samples of the dead owl were used for virus isolation and genetic characterization. The novel isolate is genetically closer to Hungarian, Greek, and Bulgarian strains from the central/southern European clade of lineage 2 than to the strains previously isolated in Slovakia. Interestingly, it carries NS3-249P, a molecular virulence determinant associated with higher neurovirulence, which has not previously been observed in Slovakia. Subsequent serological investigation of the captive owls revealed additional seropositive animals, indicating local WNV transmission. Although no WNV-positive mosquitoes were found, the presence of the WNV principal vector

Indexed as

West Nile FeverAnimalsBird DiseasesSlovakiaStrigiformesVirulenceWest Nile virusgreat grey owlvirulence determinantWest Nile viruszoological gardenzoonosis

Identifiers

PMID33920598
PMCPMC8073349
OpenAlexW3154320843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.