Evidence map›Paper›PMID 33920590›Full record

ArticleFoods (Basel, Switzerland)2021

Optimization Model of Phenolics Encapsulation Conditions for Biofortification in Fatty Acids of Animal Food Products.

Roberta Tolve, Fernanda Galgano, Nicola Condelli, Nazarena Cela, Luigi Lucini, Marisa Carmela Caruso

Open access · goldAbstract read
In one paragraph

Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.6field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Alginate-Based Encapsulation ofFood science & nutrition · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Roberta TolveSchool of Agricultural, Forestry, Food and Environmental Sciences (SAFE), University of Basilicata, Viale Dell'Ateneo Lucano 10, 85100 Potenza, Italy.ORCID 0000-0002-3384-0888
Fernanda GalganoSchool of Agricultural, Forestry, Food and Environmental Sciences (SAFE), University of Basilicata, Viale Dell'Ateneo Lucano 10, 85100 Potenza, Italy.ORCID 0000-0003-3594-6667
Nicola CondelliSchool of Agricultural, Forestry, Food and Environmental Sciences (SAFE), University of Basilicata, Viale Dell'Ateneo Lucano 10, 85100 Potenza, Italy.ORCID 0000-0002-1986-6360
Nazarena CelaSchool of Agricultural, Forestry, Food and Environmental Sciences (SAFE), University of Basilicata, Viale Dell'Ateneo Lucano 10, 85100 Potenza, Italy.ORCID 0000-0003-2230-5211
Luigi LuciniDiSTAS-Department for Sustainable Food Process, Catholic University of the Sacred Heart, 29122 Piacenza, Italy.ORCID 0000-0002-5133-9464
Marisa Carmela CarusoSchool of Agricultural, Forestry, Food and Environmental Sciences (SAFE), University of Basilicata, Viale Dell'Ateneo Lucano 10, 85100 Potenza, Italy.ORCID 0000-0002-6469-2240
University of Basilicata · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nutritional quality of animal products is strongly related to their fatty acid content and composition. Nowadays, attention is paid to the possibility of producing healthier foods of animal origin by intervening in animal feed. In this field, the use of condensed tannins as dietary supplements in animal nutrition is becoming popular due to their wide range of biological effects related, among others, to their ability to modulate the rumen biohydrogenation and biofortify, through the improvement of the fatty acids profile, the derivate food products. Unfortunately, tannins are characterized by strong astringency and low bioavailability. These disadvantages could be overcome through the microencapsulation in protective matrices. With this in mind, the optimal conditions for microencapsulation of a polyphenolic extract rich in condensed tannins by spray drying using a blend of maltodextrin (MD) and gum Arabic (GA) as shell material were investigated. For this purpose, after the extract characterization, through spectrophotometer assays and ultra-high-performance liquid chromatography-quadrupole time-of-flight (UHPLC-QTOF) mass spectrometry, a central composite design (CCD) was employed to investigate the combined effects of core:shell and MD:GA ratio on the microencapsulation process. The results obtained were used to develop second-order polynomial regression models on different responses, namely encapsulation yield, encapsulation efficiency, loading capacity, and tannin content. The formulation characterized by a core:shell ratio of 1.5:5 and MD:GA ratio of 4:6 was selected as the optimized one with a loading capacity of 17.67%, encapsulation efficiency of 76.58%, encapsulation yield of 35.69%, and tannin concentration of 14.46 g/100 g. Moreover, in vitro release under varying pH of the optimized formulation was carried out with results that could improve the use of microencapsulated condensed tannins in animal nutrition for the biofortification of derivates.

Indexed as

biofortificationcentral composite designcondensed tanninsdairy productsfatty acids profilegum Arabicmaltodextrinmicroencapsulationmilkphenolic compounds

Identifiers

PMID33920590
PMCPMC8074218
OpenAlexW3156314384

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.