Evidence map›Paper›PMID 33920570›Full record

ArticleInternational journal of environmental research and public health2021

Medication Experience and Adherence to Oral Chemotherapy: A Qualitative Study of Patients' and Health Professionals' Perspectives.

Amparo Talens, Mercedes Guilabert, Blanca Lumbreras, María Teresa Aznar, Elsa López-Pintor

Open access · goldAbstract read
In one paragraph

Article in International journal of environmental research and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Effectiveness of mHealth apps on adherence and symptoms to oral anticancer medications: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
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  4. Article
  5. Self-care agency and medication adherence among cancer patients receiving oral chemotherapy: a path analysis study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  6. Article
  7. Patient symptoms, confidence, and adherence during the first 8 weeks of targeted oral anticancer agent treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  10. Evaluation of illness perception and treatment adherence in patients taking oral chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
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  14. Immunomodulator adherence in multiple myeloma patients with lower socioeconomic status: a retrospective study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Amparo TalensPharmacy Department, Hospital General Universitario de Elda, 03600 Elda, Spain.
Mercedes GuilabertDepartment of Health Psychology, Miguel Hernandez University, 03202 Elche, Spain.ORCID 0000-0002-0706-9911
Blanca LumbrerasDepartment of Public Health, History of Science and Gynecology, Miguel Hernandez University, 03550 San Juan de Alicante, Spain.ORCID 0000-0003-1665-0860
María Teresa AznarPharmacy Department, Hospital Universitario de San Juan de Alicante, 03550 San Juan de Alicante, Spain.
Elsa López-PintorDepartment of Engineering, Area of Pharmacy and Pharmaceutical Technology, Miguel Hernandez University, 03550 San Juan de Alicante, Spain.
Universitat de Miguel Hernández d'Elx · ESHospital General de Elda · ESHospital Universitari Sant Joan D'Alacant · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lack of adherence constitutes one of the most important challenges in patients undergoing treatment with oral antineoplastic drugs (ANEO). Understanding cancer patients' experiences with respect to their medication is key for optimizing adherence and therapeutic results. We aimed to assess the medication experience (ME) in patients with cancer in treatment with ANEO, to describe the barriers and facilitators related to the disease and its treatment and to compare them with the healthcare professionals' perspectives. We carried out an exploratory qualitative study in the University Hospital of San Juan de Alicante, Spain. Three focus groups and two nominal group discussions were conducted with 23 onco-hematological patients treated with ANEO and 18 health professionals, respectively. The data were analyzed using content analyses and were eventually triangulated. The most impactful aspects in patients' ME were the presence of adverse effects; lack of information about treatment; beliefs, needs and expectations regarding medications; social and family support; and the relationship with the health professionals. Both patients and professionals agreed on considering the negative side effects and the information about treatment as the main barriers and facilitators of adherence, respectively, although the approaches differed between both profiles. The professionals offered a more technical vision while patients prioritized the emotional burden and motivation associated with the disease and medication. This study allowed us to understand the real-life experiences of patients being treated with ANEO and explore the factors which had an impact on adherence to treatment. This understanding enables professionals to have a positive influence on patients' behavior and provide individualized care plans. Pharmacists' assistance is relevant to support patients' adherence and self-management.

Indexed as

Health PersonnelMotivationFocus GroupsHumansMedication AdherenceQualitative ResearchSpainadherenceantineoplastic agentsmedication experienceoral cancer chemotherapyqualitative study

Identifiers

PMID33920570
PMCPMC8073288
OpenAlexW3155386967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.