Evidence map›Paper›PMID 33920455›Full record

ArticleInternational journal of molecular sciences2021

Human Endogenous Retrovirus (HERV)-K

Eun-Ji Ko, Mee-Sun Ock, Yung-Hyun Choi, Juan L Iovanna, Seyoung Mun, Kyudong Han, Heui-Soo Kim, Hee-Jae Cha

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  9. Review
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  11. HERV-K (HML-2) Envelope Protein Induces Mitochondrial Depolarization and Neurotoxicity via Endolysosome Iron Dyshomeostasis.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  12. Article
  13. Article
  14. The Role of Human Endogenous Retrovirus (HERV)-K119International journal of molecular sciences · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Eun-Ji KoDepartment of Parasitology and Genetics, Kosin University College of Medicine, Busan 49267, Korea.ORCID 0000-0002-3758-1019
Mee-Sun OckDepartment of Parasitology and Genetics, Kosin University College of Medicine, Busan 49267, Korea.
Yung-Hyun ChoiDepartment of Biochemistry, College of Oriental Medicine, Dongeui University, Busan 47227, Korea.ORCID 0000-0002-1454-3124
Juan L IovannaCentre de Recherche en Cancérologie de Marseille (CRCM), INSERM U1068, CNRS UMR 7258, Aix-Marseille Université and Institut Paoli-Calmettes, Parc Scientifique et Technologique de Luminy, 163 Avenue de Luminy, 13288 Marseille, France.
Seyoung MunDepartment of Nanobiomedical Science, Dankook University, Cheonan 31116, Korea.
Kyudong HanCenter for Bio-Medical Engineering Core Facility, Dankook University, Cheonan 31116, Korea.ORCID 0000-0001-6791-2408
Heui-Soo KimDepartment of Biological Sciences, College of Natural Sciences, Pusan National University, Busan 46241, Korea.
Hee-Jae ChaDepartment of Parasitology and Genetics, Kosin University College of Medicine, Busan 49267, Korea.ORCID 0000-0002-6963-2685
Dankook University · KRKosin University · KRPusan National University · KRCentre National de la Recherche Scientifique · FRDong-Eui University · KR

Funding

Korean Government NRF-2016R1D1A3B01007444
6 · The paper itself

Abstract

Human endogenous retroviruses (HERVs) are suggested to be involved in the development of certain diseases, especially cancers. To elucidate the function of HERV-K Env protein in cancers, an HERV-K

Indexed as

CarcinogenesisColorectal NeoplasmsEndogenous RetrovirusesNeoplasm ProteinsNuclear Receptor Subfamily 4, Group A, Member 2Gene Knockdown TechniquesGene Products, envHCT116 CellsHumansGene Products, envNeoplasm ProteinsNR4A2 protein, humanNuclear Receptor Subfamily 4, Group A, Member 2colorectal cancerCRISPR-Cas9HERV-K EnvNUPR1ROStumor suppressor

Identifiers

PMID33920455
PMCPMC8070087
OpenAlexW3154323955

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.