Evidence map›Paper›PMID 33920428›Full record

ReviewInternational journal of molecular sciences2021

Endocrine-Disrupting Chemicals and Infectious Diseases: From Endocrine Disruption to Immunosuppression.

Elikanah Olusayo Adegoke, Md Saidur Rahman, Yoo-Jin Park, Young Ju Kim, Myung-Geol Pang

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Elikanah Olusayo AdegokeDepartment of Animal Science & Technology and BET Research Institute, Chung-Ang University, Anseong 17546, Korea.
Md Saidur RahmanDepartment of Animal Science & Technology and BET Research Institute, Chung-Ang University, Anseong 17546, Korea.ORCID 0000-0003-4583-8731
Yoo-Jin ParkDepartment of Animal Science & Technology and BET Research Institute, Chung-Ang University, Anseong 17546, Korea.
Young Ju KimDepartment of Obstetrics and Gynecology, College of Medicine, Ewha Womans University, Seoul 07985, Korea.ORCID 0000-0002-3153-3008
Myung-Geol PangDepartment of Animal Science & Technology and BET Research Institute, Chung-Ang University, Anseong 17546, Korea.ORCID 0000-0003-2019-3789
Chung-Ang University · KREwha Womans University · KR

Funding

National Research Foundation of Korea 2017H1D3A1A02013844National Research Foundation of Korea 2019H1D3A1A01071117National Research Foundation of Korea NRF-2018R1A6A1A03025159,
6 · The paper itself

Abstract

Endocrine-disrupting chemicals (EDCs) are hormonally active compounds in the environment that interfere with the body's endocrine system and consequently produce adverse health effects. Despite persistent public health concerns, EDCs remain important components of common consumer products, thus representing ubiquitous contaminants to humans. While scientific evidence confirmed their contribution to the severity of Influenza A virus (H1N1) in the animal model, their roles in susceptibility and clinical outcome of the coronavirus disease (COVID-19) cannot be underestimated. Since its emergence in late 2019, clinical reports on COVID-19 have confirmed that severe disease and death occur in persons aged ≥65 years and those with underlying comorbidities. Major comorbidities of COVID-19 include diabetes, obesity, cardiovascular disease, hypertension, cancer, and kidney and liver diseases. Meanwhile, long-term exposure to EDCs contributes significantly to the onset and progression of these comorbid diseases. Besides, EDCs play vital roles in the disruption of the body's immune system. Here, we review the recent literature on the roles of EDCs in comorbidities contributing to COVID-19 mortality, impacts of EDCs on the immune system, and recent articles linking EDCs to COVID-19 risks. We also recommend methodologies that could be adopted to comprehensively study the role of EDCs in COVID-19 risk.

Indexed as

Communicable DiseasesComorbidityCOVID-19Endocrine DisruptorsEndocrine System DiseasesHumansImmunosuppression TherapyEndocrine Disruptorscomorbid diseasesCOVID-19endocrine disrupting chemicalsimmune dysfunction

Identifiers

PMID33920428
PMCPMC8069594
OpenAlexW3154925272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.