Evidence map›Paper›PMID 33920369›Full record

ReviewAntibiotics (Basel, Switzerland)2021

Phage Therapy in Veterinary Medicine.

Rosa Loponte, Ugo Pagnini, Giuseppe Iovane, Giuseppe Pisanelli

Open access · goldAbstract readReview
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. One health (Amsterdam, Netherlands) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Phage Therapy for a Refractory and Multidrug-resistant Equine Surgical Site Infection.International journal of veterinary science and medicine · 2026
    Article
  9. Review
  10. Review
  11. Efficacy ofMicrobiology spectrum · 2025
    Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. The potential of using bacteriophages targetingFrontiers in microbiology · 2025
    Review
  18. Editorial: Prevalence and transmission of emerging and replicating animal viruses.Frontiers in cellular and infection microbiology · 2025
    Article
  19. Current understanding of theFrontiers in veterinary science · 2025
    Review
  20. Successful phage-antibiotic therapy ofThe veterinary quarterly · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Rosa LoponteDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, via Federico Delpino, 1, 80137 Naples, Italy.
Ugo PagniniDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, via Federico Delpino, 1, 80137 Naples, Italy.
Giuseppe IovaneDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, via Federico Delpino, 1, 80137 Naples, Italy.
Giuseppe PisanelliDepartment of Veterinary Medicine and Animal Production, University of Naples Federico II, via Federico Delpino, 1, 80137 Naples, Italy.ORCID 0000-0002-8229-6882
University of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To overcome the obstacle of antimicrobial resistance, researchers are investigating the use of phage therapy as an alternative and/or supplementation to antibiotics to treat and prevent infections both in humans and in animals. In the first part of this review, we describe the unique biological characteristics of bacteriophages and the crucial aspects influencing the success of phage therapy. However, despite their efficacy and safety, there is still no specific legislation that regulates their use. In the second part of this review, we describe the comprehensive research done in the past and recent years to address the use of phage therapy for the treatment and prevention of bacterial disease affecting domestic animals as an alternative to antibiotic treatments. While in farm animals, phage therapy efficacy perspectives have been widely studied in vitro and in vivo, especially for zoonoses and diseases linked to economic losses (such as mastitis), in pets, studies are still few and rather recent.

Indexed as

alternative to antibioticsbacteriophagespetsphage therapyveterinary medicine

Identifiers

PMID33920369
PMCPMC8069180
OpenAlexW3154780188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.