Evidence map›Paper›PMID 33920244›Full record

ReviewAnimals : an open access journal from MDPI2021

Pain at the Slaughterhouse in Ruminants with a Focus on the Neurobiology of Sensitisation.

Daniel Mota-Rojas, Fabio Napolitano, Ana Strappini, Agustín Orihuela, Marcelo Daniel Ghezzi, Ismael Hernández-Ávalos, Patricia Mora-Medina, Alexandra L Whittaker

Abstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Slaughtering of Water Buffalo (Animals : an open access journal from MDPI · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Application of Electroencephalography in Preslaughter Management: A Review.Animals : an open access journal from MDPI · 2022
    Review
  11. Review
  12. Review
  13. Frontiers in veterinary science · 2022
    Article
  14. Review
  15. Review
  16. Review
  17. Physiological and Behavioral Mechanisms of Thermoregulation in Mammals.Animals : an open access journal from MDPI · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniel Mota-RojasNeurophysiology, Behavior and Animal Welfare Assessment, DPAA, Universidad Autónoma Metropolitana, Xochimilco Campus, 04960 Ciudad de México, Mexico.ORCID 0000-0003-0562-0367
Fabio NapolitanoScuola di Scienze Agrarie, Forestali, Alimentari ed Ambientali, Università degli Studi della Basilicata, 85100 Potenza, Italy.ORCID 0000-0002-7169-5300
Ana StrappiniAnimal Science Institute, Faculty of Veterinary Sciences, Universidad Austral de Chile, 5090000 Valdivia, Chile.ORCID 0000-0002-7203-3472
Agustín OrihuelaFacultad de Ciencias Agropecuarias, Universidad Autónoma del Estado de Morelos, 62209 Cuernavaca, Mexico.ORCID 0000-0003-1226-7717
Marcelo Daniel GhezziAnimal Welfare Area, Faculty of Veterinary Sciences (FCV), Universidad Nacional del Centro de la Provincia de Buenos Aires (UNCPBA), 7000 Buenos Aires, Argentina.ORCID 0000-0003-2519-9522
Ismael Hernández-ÁvalosFacultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México (UNAM), 54714 Cuautitlan Izcalli, Mexico.ORCID 0000-0003-4271-2906
Patricia Mora-MedinaFacultad de Estudios Superiores Cuautitlán, Universidad Nacional Autónoma de México (UNAM), 54714 Cuautitlan Izcalli, Mexico.ORCID 0000-0002-8153-8210
Alexandra L WhittakerSchool of Animal and Veterinary Sciences, University of Adelaide, Roseworthy, SA 5116, Australia.ORCID 0000-0001-9011-8296

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We pose, based on a neurobiological examination, that events that occur around the time of slaughter have the potential to intensify the pain response, through the processes of sensitisation and enhanced transmission. Sensitisation, or an enhanced response to painful stimuli, is a well-discussed phenomenon in the human medical literature, which can arise from previous injury to an area, inflammatory reactions, or previous overstimulation of the stress axes. A number of events that occur prior to arrival at, or in the slaughterhouse, may lead to presence of these factors. This includes previous on-farm pathology, injuries arising from transport and handling and lack of habituation to humans. Whilst there is limited evidence of a direct effect of these on the processes of sensitisation in animals at slaughter, by analogy with the human neurobiology literature the connection seems plausible. In this review a neurobiological approach is taken to discuss this hypothesis in the light of basic science, and extrapolations from existing literature on the slaughter of ruminants. To confirm the postulated link between events at slaughter, and processes of hypersensitisation, further dedicated study is required.

Indexed as

abattoiranimal welfarecattleHalalKosherpainriver buffalosensitisationShechitastunning

Identifiers

PMID33920244
PMCPMC8068923

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.