Evidence map›Paper›PMID 33920242›Full record

ArticlePharmaceutics2021

Development of a Nanostructured Lipid Carrier (NLC) by a Low-Energy Method, Comparison of Release Kinetics and Molecular Dynamics Simulation.

Andrea C Ortiz, Osvaldo Yañez, Edison Salas-Huenuleo, Javier O Morales

Abstract read
In one paragraph

Article in Pharmaceutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

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  7. DualAntioxidants (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrea C OrtizDepartment of Pharmaceutical Science and Technology, School of Chemical and Pharmaceutical Sciences, Universidad de Chile, Santiago 8380494, Chile.
Osvaldo YañezDepartment of Pharmaceutical Science and Technology, School of Chemical and Pharmaceutical Sciences, Universidad de Chile, Santiago 8380494, Chile.ORCID 0000-0001-8993-9353
Edison Salas-HuenuleoAdvanced Integrated Technologies (AINTECH), Santiago 7821207, Chile.ORCID 0000-0003-4355-5252
Javier O MoralesDepartment of Pharmaceutical Science and Technology, School of Chemical and Pharmaceutical Sciences, Universidad de Chile, Santiago 8380494, Chile.ORCID 0000-0002-3190-2168

Funding

ANID/FONDAP 15130011ANID/PCI REDI170653ANID/PIA ACT192144Comisión Nacional de Investigación Científica y Tecnológica 21180654Fondo Nacional de Desarrollo Científico y Tecnológico 1181689
6 · The paper itself

Abstract

Lipid nanocarriers have a great potential for improving the physicochemical characteristics and behavior of poorly water-soluble drugs, such as aqueous dispersibility and oral bioavailability. This investigation presents a novel nanostructured lipid carrier (NLC) based on a mixture of solid lipid glycerides, fatty acid esters of PEG 1500 (Gelucire

Indexed as

drug releaseFranz’s cellsGelucire® 44/14lipid nanoparticlelow-energy methodmolecular dynamics simulationsNLC

Identifiers

PMID33920242
PMCPMC8070589

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.