Evidence map›Paper›PMID 33920240›Full record

ArticleViruses2021

The Development of Bacteriophage Resistance in

Dimitrios Skliros, Panos G Kalatzis, Chrysanthi Kalloniati, Fotios Komaitis, Sokratis Papathanasiou, Evangelia D Kouri, Michael K Udvardi, Constantina Kokkari, Pantelis Katharios, Emmanouil Flemetakis

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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  3. Article
  4. Antivirulence Activity and Therapeutic Potential of JumboJournal of microbiology and biotechnology · 2025
    Article
  5. Article
  6. Review
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Dimitrios SklirosLaboratory of Molecular Biology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 1855 Athens, Greece.ORCID 0000-0001-9753-2510
Panos G KalatzisDepartment of Biology, Marine Biological Section, University of Copenhagen, 3000 Helsingør, Denmark.ORCID 0000-0003-3029-783X
Chrysanthi KalloniatiLaboratory of Molecular Biology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 1855 Athens, Greece.
Fotios KomaitisLaboratory of Molecular Biology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 1855 Athens, Greece.
Sokratis PapathanasiouLaboratory of Molecular Biology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 1855 Athens, Greece.
Evangelia D KouriThe Noble Research Institute, 2510 Sam Noble Pkwy, Ardmore, OK 73401, USA.
Michael K UdvardiThe Noble Research Institute, 2510 Sam Noble Pkwy, Ardmore, OK 73401, USA.
Constantina KokkariInstitute of Marine Biology, Biotechnology and Aquaculture, Hellenic Centre for Marine Research, 71500 Heraklion, Greece.
Pantelis KathariosInstitute of Marine Biology, Biotechnology and Aquaculture, Hellenic Centre for Marine Research, 71500 Heraklion, Greece.ORCID 0000-0001-9905-5068
Emmanouil FlemetakisLaboratory of Molecular Biology, Department of Biotechnology, School of Applied Biology and Biotechnology, Agricultural University of Athens, 1855 Athens, Greece.
Agricultural University of Athens · GRHellenic Centre for Marine Research · GRNoble Research Institute · USUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lytic bacteriophages have been well documented to play a pivotal role in microbial ecology due to their complex interactions with bacterial species, especially in aquatic habitats. Although the use of phages as antimicrobial agents, known as phage therapy, in the aquatic environment has been increasing, recent research has revealed drawbacks due to the development of phage-resistant strains among Gram-negative species. Acquired phage resistance in marine

Indexed as

Adaptation, PhysiologicalBacteriophagesDrug Resistance, BacterialGene Expression ProfilingGenome, ViralGenomicsHost Microbial InteractionsMetabolic Networks and PathwaysMetabolomicsPhage TherapyPhylogenyVibrio alginolyticusacquired phage resistancebacteriophageshost metabolismhost–phage interactionmetabolic reprogrammingreceptorstransportersVibrio alginolyticus

Identifiers

PMID33920240
PMCPMC8069663
OpenAlexW3153681635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.