Evidence map›Paper›PMID 33920203›Full record

ArticleBiomolecules2021

α-Tocopherol Attenuates Oxidative Phosphorylation of CD34

Laura Rodriguez, Pascale Duchez, Nicolas Touya, Christelle Debeissat, Amélie V Guitart, Jean-Max Pasquet, Marija Vlaski-Lafarge, Philippe Brunet de la Grange, Zoran Ivanovic

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Laura RodriguezEtablissement Français du Sang Nouvelle Aquitaine, Place Amélie Raba Léon, CS22010, CEDEX, 33075 Bordeaux, France.ORCID 0000-0001-8968-8873
Pascale DuchezEtablissement Français du Sang Nouvelle Aquitaine, Place Amélie Raba Léon, CS22010, CEDEX, 33075 Bordeaux, France.
Nicolas TouyaEtablissement Français du Sang Nouvelle Aquitaine, Place Amélie Raba Léon, CS22010, CEDEX, 33075 Bordeaux, France.ORCID 0000-0003-0140-6371
Christelle DebeissatInserm Bordeaux UMR 1035, 33000 Bordeaux, France.
Amélie V GuitartInserm Bordeaux UMR 1035, 33000 Bordeaux, France.ORCID 0000-0002-1451-8789
Jean-Max PasquetInserm Bordeaux UMR 1035, 33000 Bordeaux, France.ORCID 0000-0002-1345-3776
Marija Vlaski-LafargeEtablissement Français du Sang Nouvelle Aquitaine, Place Amélie Raba Léon, CS22010, CEDEX, 33075 Bordeaux, France.
Philippe Brunet de la GrangeEtablissement Français du Sang Nouvelle Aquitaine, Place Amélie Raba Léon, CS22010, CEDEX, 33075 Bordeaux, France.
Zoran IvanovicEtablissement Français du Sang Nouvelle Aquitaine, Place Amélie Raba Léon, CS22010, CEDEX, 33075 Bordeaux, France.
Université de Bordeaux · FR

Funding

Etablissement Français du Sang regular regional research budget 2017, 2018, 2019, 2020
6 · The paper itself

Abstract

Alpha tocopherol acetate (αTOA) is an analogue of alpha tocopherol (αTOC) that exists in the form of an injectable drug. In the context of the metabolic hypothesis of stem cells, we studied the impact of αTOA on the metabolic energetic profile and functional properties of hematopoietic stem and progenitor cells. In ex vivo experiments performed on cord blood CD34

Indexed as

Oxidative PhosphorylationResting Phase, Cell Cyclealpha-TocopherolAnimalsAntigens, CD34AntioxidantsBasic Helix-Loop-Helix ProteinsCells, CulturedCell Self RenewalEndothelial PAS Domain-Containing Protein 1Hematopoietic Stem CellsHumansMiceMice, Inbred C57BLMice, SCIDReactive Oxygen Speciesalpha-TocopherolAntigens, CD34AntioxidantsBasic Helix-Loop-Helix ProteinsEndothelial PAS Domain-Containing Protein 1Reactive Oxygen SpeciesVitaminselectron transport chainenergetic metabolismhematopoietic progenitorshematopoietic stem cellsoxidative phosphorylationproliferative capacityquiescenceα-tocopherol acetate

Identifiers

PMID33920203
PMCPMC8070309
OpenAlexW3153200887

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.