Evidence map›Paper›PMID 33920166›Full record

ArticleMicroorganisms2021

Comparison of Clinical, Laboratory and Immune Characteristics of the Monophasic and Biphasic Course of Tick-Borne Encephalitis.

Petra Bogovič, Stanka Lotrič-Furlan, Tatjana Avšič-Županc, Miša Korva, Andrej Kastrin, Lara Lusa, Klemen Strle, Franc Strle

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Trial
  2. Diagnostic value of RT-PCR for detection of tick-borne encephalitis virus RNA in cerebrospinal fluid.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  3. Tick-borne encephalitis in Norway: A cohort study of clinical course and health-related quality of life at three- and twelve-month follow-up.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Article
  4. Clinical characteristics and factors affecting disease severity in hospitalized tick-borne encephalitis patients in Norway from 2018 to 2022.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2024
    Observational
  5. Article
  6. Article
  7. Tick-Borne Encephalitis Vaccine: Recommendations of the Advisory Committee on Immunization Practices, United States, 2023.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Petra BogovičDepartment of Infectious Diseases, University Medical Centre Ljubljana, Japljeva 2, 1525 Ljubljana, Slovenia.
Stanka Lotrič-FurlanDepartment of Infectious Diseases, University Medical Centre Ljubljana, Japljeva 2, 1525 Ljubljana, Slovenia.
Tatjana Avšič-ŽupancFaculty of Medicine, Institute for Microbiology and Immunology, University of Ljubljana, Zaloška 4, 1000 Ljubljana, Slovenia.ORCID 0000-0001-6243-0688
Miša KorvaFaculty of Medicine, Institute for Microbiology and Immunology, University of Ljubljana, Zaloška 4, 1000 Ljubljana, Slovenia.
Andrej KastrinFaculty of Medicine, Institute for Biostatistics and Medical Informatics, University of Ljubljana, Vrazov trg 2, 1000 Ljubljana, Slovenia.ORCID 0000-0002-3495-0165
Lara LusaFaculty of Medicine, Institute for Biostatistics and Medical Informatics, University of Ljubljana, Vrazov trg 2, 1000 Ljubljana, Slovenia.
Klemen StrleLaboratory of Microbial Pathogenesis and Immunology, Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12208, USA.
Franc StrleDepartment of Infectious Diseases, University Medical Centre Ljubljana, Japljeva 2, 1525 Ljubljana, Slovenia.ORCID 0000-0003-4163-0503
University of Ljubljana · SILjubljana University Medical Centre · SINew York State Department of Health · USUniversity of Primorska · SI

Funding

Defining Host Genetic Factors in Adverse Clinical Outcomes in Lyme DiseaseR21AI144916 · NIAID · WADSWORTH CENTER · PI LIN, YI-PIN, STRLE, KLEMEN · 2019 to 2020
$449k
NIH HHS R21 AI144916Slovenian Research Agency P3-0296, J3-1744, and J3-8195
6 · The paper itself

Abstract

The biphasic course of tick-borne encephalitis (TBE) is well described, but information on the monophasic course is limited. We assessed and compared the clinical presentation, laboratory findings, and immune responses in 705 adult TBE patients: 283 with monophasic and 422 with biphasic course. Patients with the monophasic course were significantly (

Indexed as

adaptive immune responsesbiphasic coursecerebrospinal fluidchemokinescytokinesinnate immune responseslong-term outcomemonophasic coursetick-borne encephalitis

Identifiers

PMID33920166
PMCPMC8070281
OpenAlexW3154254335

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.