Evidence map›Paper›PMID 33920046›Full record

ArticleInternational journal of molecular sciences2021

Biohybrid Bovine Bone Matrix for Controlled Release of Mesenchymal Stem/Stromal Cell Lyosecretome: A Device for Bone Regeneration.

Elia Bari, Ilaria Roato, Giuseppe Perale, Filippo Rossi, Tullio Genova, Federico Mussano, Riccardo Ferracini, Marzio Sorlini, Maria Luisa Torre, Sara Perteghella

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
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  5. Review
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  7. Review
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  11. Article
  12. The Role of MSCs and Cell Fusion in Tissue Regeneration.International journal of molecular sciences · 2021
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Elia BariDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, I-27100 Pavia, Italy.ORCID 0000-0003-0241-0620
Ilaria RoatoDepartment of Surgical Sciences, CIR-Dental School, University of Torino, Via Nizza 230, I-10126 Torino, Italy.ORCID 0000-0003-3029-4743
Giuseppe PeraleIndustrie Biomediche Insubri SA, Via Cantonale 67, CH-6805 Mezzovico-Vira, Switzerland.
Filippo RossiDepartment of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Via Mancinelli 7, I-20131 Milano, Italy.ORCID 0000-0003-2665-120X
Tullio GenovaDepartment of Life Sciences and Systems Biology, University of Torino, Via Accademia Albertina 13, I-10123 Torino, Italy.ORCID 0000-0001-7824-8389
Federico MussanoDepartment of Surgical Sciences, CIR-Dental School, University of Torino, Via Nizza 230, I-10126 Torino, Italy.ORCID 0000-0001-5800-0749
Riccardo FerraciniDepartment of Surgical Sciences and Integrated Diagnostics, University of Genova, Viale Benedetto XV 6, I-16132 Genova, Italy.ORCID 0000-0001-7654-0327
Marzio SorliniSUPSI-Department of Innovative Technologies, Lugano University Centre, Campus Est, Via la Santa 1, CH-6962 Viganello, Switzerland.
Maria Luisa TorreDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, I-27100 Pavia, Italy.ORCID 0000-0001-8062-6836
Sara PerteghellaDepartment of Drug Sciences, University of Pavia, Viale Taramelli 12, I-27100 Pavia, Italy.ORCID 0000-0003-1128-7636

Funding

Interreg V-A Italy-Switzerland 2014-2020 ATEx-Advanced Therapies Experiences. Project ID 637541.
6 · The paper itself

Abstract

SmartBone

Indexed as

Mesenchymal Stem Cell TransplantationAnimalsBone MatrixBone RegenerationBone SubstitutesCattleCell DifferentiationDelayed-Action PreparationsExtracellular VesiclesHumansMesenchymal Stem CellsOsteoblastsOsteogenesisPlastic Surgery ProceduresBone SubstitutesDelayed-Action Preparationsbone graftingbone regenerationmesenchymal stem cellsMSC-exosomesMSC-extracellular vesiclesMSC-secretome

Identifiers

PMID33920046
PMCPMC8071018

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.