Evidence map›Paper›PMID 33920000›Full record

ArticleAntibiotics (Basel, Switzerland)2021

Lorenzo Suigo, Michaelle Chojnacki, Carlo Zanotto, Victor Sebastián-Pérez, Carlo De Giuli Morghen, Andrea Casiraghi, Paul M Dunman, Ermanno Valoti, Valentina Straniero

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Construction of a linezolid-resistant strain of methicillin-susceptibleFrontiers in cellular and infection microbiology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Lorenzo SuigoDipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Luigi Mangiagalli 25, 20133 Milano, Italy.ORCID 0000-0002-8958-1547
Michaelle ChojnackiDepartment of Microbiology and Immunology, University of Rochester Medical Center, 601 Elmwood Ave., Rochester, NY 14642, USA.
Carlo ZanottoDipartimento di Biotecnologie Mediche e Medicina Traslazionale, Università degli Studi di Milano, Via Vanvitelli 32, 20129 Milano, Italy.
Victor Sebastián-PérezExscientia, The Schrödinger Building, Oxford Science Park, Oxford OX4 4GE, UK.
Carlo De Giuli MorghenDepartment of Chemical-Pharmaceutical and Biomolecular Technologies, Catholic University "Our Lady of Good Counsel", Rr. Dritan Hoxha, 1025 Tirana, Albania.
Andrea CasiraghiDipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Luigi Mangiagalli 25, 20133 Milano, Italy.
Paul M DunmanDepartment of Microbiology and Immunology, University of Rochester Medical Center, 601 Elmwood Ave., Rochester, NY 14642, USA.
Ermanno ValotiDipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Luigi Mangiagalli 25, 20133 Milano, Italy.ORCID 0000-0002-5608-3875
Valentina StranieroDipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Luigi Mangiagalli 25, 20133 Milano, Italy.ORCID 0000-0002-5089-0879
University of Milan · ITUniversity of Rochester Medical Center · USCatholic University Our Lady of Good Counsel · AL

Funding

Antibacterial inhibitors of RnpAR01AI134685 · NIAID · UNIVERSITY OF ROCHESTER · PI DUNMAN, PAUL M. · 2018 to 2022
$3.6M
Staphylococcus aureus RNA turnover propertiesR01AI073780 · NIAID · UNIVERSITY OF ROCHESTER · PI DUNMAN, PAUL M. · 2008 to 2011
$1.5M
NIAID NIH HHS R01 AI073780NIAID NIH HHS R01 AI134685
6 · The paper itself

Abstract

Antibiotic resistance is spreading worldwide and it has become one of the most important issues in modern medicine. In this context, the bacterial RNA degradation and processing machinery are essential processes for bacterial viability that may be exploited for antimicrobial therapy. In

Indexed as

antibiotic resistanceantimicrobial activitygram-positive bacteriaMRSARNA degradation machineryRnpA inhibitorsUAMS-1

Identifiers

PMID33920000
PMCPMC8071009
OpenAlexW3154537003

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.