Evidence map›Paper›PMID 33919990›Full record

ArticleInternational journal of molecular sciences2021

Protective Effect of Quercetin on Sodium Iodate-Induced Retinal Apoptosis through the Reactive Oxygen Species-Mediated Mitochondrion-Dependent Pathway.

Yuan-Yen Chang, Yi-Ju Lee, Min-Yen Hsu, Meilin Wang, Shang-Chun Tsou, Ching-Chung Chen, Jer-An Lin, Yai-Ping Hsiao, Hui-Wen Lin

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 41 citations in OpenAlex.

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  9. Frontiers in pharmacology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Yuan-Yen ChangDepartment of Microbiology and Immunology, School of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan.
Yi-Ju LeeDepartment of Pathology, Chung Shan Medical University Hospital, Chung Shan Medical University, Taichung 40201, Taiwan.
Min-Yen HsuDepartment of Ophthalmology, Chung Shan Medical University Hospital, Taichung 40201, Taiwan.ORCID 0000-0002-5488-4257
Meilin WangDepartment of Microbiology and Immunology, School of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan.
Shang-Chun TsouDepartment of Biomedical Sciences, Chung Shan Medical University, Taichung 40201, Taiwan.
Ching-Chung ChenDepartment of Optometry, Asia University, Taichung 41354, Taiwan.
Jer-An LinGraduate Institute of Food Safety, National Chung Hsing University, Taichung 40201, Taiwan.ORCID 0000-0002-1362-1370
Yai-Ping HsiaoDepartment of Ophthalmology, Chung Shan Medical University Hospital, Taichung 40201, Taiwan.
Hui-Wen LinDepartment of Optometry, Asia University, Taichung 41354, Taiwan.ORCID 0000-0002-0738-8509
Chung Shan Medical University Hospital · TWAsia University · TWNational Chung Hsing University · TWChung Shan Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related macular degeneration (AMD) leads to gradual central vision loss and is the third leading cause of irreversible blindness worldwide. The underlying mechanisms for this progressive neurodegenerative disease remain unclear and there is currently no preventive treatment for dry AMD. Sodium iodate (NaIO

Indexed as

Apoptosisbcl-2-Associated X ProteinCaspase 3Cell LineGene Expression RegulationHumansIodatesMacular DegenerationMitochondriaPoly(ADP-ribose) PolymerasesQuercetinReactive Oxygen SpeciesRetinaRetinal DiseasesRetinal Pigment EpitheliumSignal Transductionbcl-2-Associated X ProteinCaspase 3IodatesPoly(ADP-ribose) PolymerasesQuercetinReactive Oxygen Speciessodium iodateage-related macular degenerationapoptosishuman retinal pigment epitheliummitochondrial membrane potentialquercetinsodium iodate

Identifiers

PMID33919990
PMCPMC8071060
OpenAlexW3152673454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.