ArticleMaterials (Basel, Switzerland)2021
Inverse 3D Printing with Variations of the Strand Width of the Resulting Scaffolds for Bone Replacement.
Article in Materials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Additive manufacturing of poly (lactic acid)/hydroxyapatite/carbon nanotubes biocomposites for fibroblast cell proliferation.Scientific reports · 2023Article
- Review
- Adjustment of Micro- and Macroporosity of ß-TCP Scaffolds Using Solid-Stabilized Foams as Bone Replacement.Bioengineering (Basel, Switzerland) · 2023Article
- Alternative Geometries for 3D Bioprinting of Calcium Phosphate Cement as Bone Substitute.Biomedicines · 2022Article
- About 3D Printability of Thermoplastic Collagen for Biomedical Applications.Bioengineering (Basel, Switzerland) · 2022Article
- Influence of 3D Printing Parameters on the Mechanical Stability of PCL Scaffolds and the Proliferation Behavior of Bone Cells.Materials (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study was to vary the wall thicknesses and pore sizes of inversely printed 3D molded bodies. Wall thicknesses were varied from 1500 to 2000 to 2500 µm. The pores had sizes of 500, 750 and 1000 µm. The sacrificial structures were fabricated from polylactide (PLA) using fused deposition modeling (FDM). To obtain the final bioceramic scaffolds, a water-based slurry was filled into the PLA molds. The PLA sacrificial molds were burned out at approximately 450 °C for 4 h. Subsequently, the samples were sintered at 1250 °C for at least 4 h. The scaffolds were mechanically characterized (native and after incubation in simulated body fluid (SBF) for 28 days). In addition, the biocompatibility was assessed by live/dead staining. The scaffolds with a strand spacing of 500 µm showed the highest compressive strength; there was no significant difference in compressive strength regardless of pore size. The specimens with 1000 µm pore size showed a significant dependence on strand width. Thus, the specimens (1000 µm pores) with 2500 µm wall thickness showed the highest compressive strength of 5.97 + 0.89 MPa. While the 1000(1500) showed a value of 2.90 + 0.67 MPa and the 1000(2000) of 3.49 + 1.16 MPa. As expected for beta-Tricalciumphosphate (β-TCP), very good biocompatibility was observed with increasing cell numbers over the experimental period.
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