ReviewPharmaceuticals (Basel, Switzerland)2021
3D Bioprinting of Functional Skin Substitutes: From Current Achievements to Future Goals.
Review in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Article
- Innovations in skin microphysiological systems for nonclinical testing and FDA modernization.Microsystems & nanoengineering · 2026Review
- AlternativeExpert reviews in molecular medicine · 2026Review
- Lipid-Based Nanocarriers as a Promising Delivery System in the Management of Acne.Current pharmaceutical design · 2026Review
- Innovate to heal: 3D bioprinting tackles epidermolysis bullosa.Annals of medicine and surgery (2012) · 2025Article
- Skin substitutes: from conventional to 3D bioprinting.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025Review
- Vascularized skin tissue models featuring adipose cell spheroid-laden GelMA hydrogels.Materials today. Bio · 2025Article
- 3D Bioprinting: Shaping the Future of Periodontal Tissue Regeneration and Disease Management.Cureus · 2025Review
- Improving Thermosensitive Bioink Scaffold Fabrication with a Temperature-Regulated Printhead in Robot-AssistedACS omega · 2024Article
- Article
- Bioengineering Skin Substitutes for Wound Management-Perspectives and Challenges.International journal of molecular sciences · 2024Review
- Angiogenesis, hemocompatibility and bactericidal effect of bioactive natural polymer-based bilayer adhesive skin substitute for infected burned wound healing.Bioactive materials · 2023Article
- Innovations in Stem Cell Therapy for Diabetic Wound Healing.Advances in wound care · 2023Review
- Perspectives on the Current State of Bioprinted Skin Substitutes for Wound Healing.Biomedicines · 2023Review
- Modelling the Complexity of Human Skin In Vitro.Biomedicines · 2023Review
- Nanocomposite Bioprinting for Tissue Engineering Applications.Gels (Basel, Switzerland) · 2023Review
- Research progress and challenges of bioprinting in wound dressing and healing: Bibliometrics-based analysis and perspectives.International journal of bioprinting · 2023Review
- Toward better drug development: Three-dimensional bioprinting in toxicological research.International journal of bioprinting · 2023Review
- Functionalised-biomatrix for wound healing and cutaneous regeneration: future impactful medical products in clinical translation and precision medicine.Frontiers in bioengineering and biotechnology · 2023Review
- 219Three-dimensional printing as a cutting-edge, versatile and personalizable vascular stent manufacturing procedure: Toward tailor-made medical devices.International journal of bioprinting · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The aim of this review is to present 3D bioprinting of skin substitutes as an efficient approach of managing skin injuries. From a clinical point of view, classic treatments only provide physical protection from the environment, and existing engineered scaffolds, albeit acting as a physical support for cells, fail to overcome needs, such as neovascularisation. In the present work, the basic principles of bioprinting, together with the most popular approaches and choices of biomaterials for 3D-printed skin construct production, are explained, as well as the main advantages over other production methods. Moreover, the development of this technology is described in a chronological manner through examples of relevant experimental work in the last two decades: from the pioneers Lee et al. to the latest advances and different innovative strategies carried out lately to overcome the well-known challenges in tissue engineering of skin. In general, this technology has a huge potential to offer, although a multidisciplinary effort is required to optimise designs, biomaterials and production processes.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.