Evidence map›Paper›PMID 33919808›Full record

ReviewCells2021

Considerations to Model Heart Disease in Women with Preeclampsia and Cardiovascular Disease.

Clara Liu Chung Ming, Kimberly Sesperez, Eitan Ben-Sefer, David Arpon, Kristine McGrath, Lana McClements, Carmine Gentile

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Clara Liu Chung MingSchool of Biomedical Engineering/FEIT, University of Technology Sydney, Sydney, NSW 2007, Australia.
Kimberly SesperezSchool of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.
Eitan Ben-SeferSchool of Biomedical Engineering/FEIT, University of Technology Sydney, Sydney, NSW 2007, Australia.
David ArponSchool of Biomedical Engineering/FEIT, University of Technology Sydney, Sydney, NSW 2007, Australia.ORCID 0000-0003-3400-5689
Kristine McGrathSchool of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.ORCID 0000-0002-6244-3929
Lana McClementsSchool of Life Sciences, Faculty of Science, University of Technology Sydney, Sydney, NSW 2007, Australia.ORCID 0000-0002-4911-1014
Carmine GentileSchool of Biomedical Engineering/FEIT, University of Technology Sydney, Sydney, NSW 2007, Australia.ORCID 0000-0002-3689-4275
University of Technology Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Preeclampsia is a multifactorial cardiovascular disorder diagnosed after 20 weeks of gestation, and is the leading cause of death for both mothers and babies in pregnancy. The pathophysiology remains poorly understood due to the variability and unpredictability of disease manifestation when studied in animal models. After preeclampsia, both mothers and offspring have a higher risk of cardiovascular disease (CVD), including myocardial infarction or heart attack and heart failure (HF). Myocardial infarction is an acute myocardial damage that can be treated through reperfusion; however, this therapeutic approach leads to ischemic/reperfusion injury (IRI), often leading to HF. In this review, we compared the current in vivo, in vitro and ex vivo model systems used to study preeclampsia, IRI and HF. Future studies aiming at evaluating CVD in preeclampsia patients could benefit from novel models that better mimic the complex scenario described in this article.

Indexed as

Models, BiologicalCardiovascular DiseasesFemaleHeart FailureHumansMicrofluidicsMyocardial Reperfusion InjuryPre-EclampsiaPregnancycardiovascular diseaseex vivo model systemheart failurein vitro model systemin vivo model systemischemic/reperfusion injurypreeclampsia

Identifiers

PMID33919808
PMCPMC8070848
OpenAlexW3153236285

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.