Evidence map›Paper›PMID 33919768›Full record

ArticleNanomaterials (Basel, Switzerland)2021

The Role of Polymeric Coatings for a Safe-by-Design Development of Biomedical Gold Nanoparticles Assessed in Zebrafish Embryo.

Pamela Floris, Stefania Garbujo, Gabriele Rolla, Marco Giustra, Lucia Salvioni, Tiziano Catelani, Miriam Colombo, Paride Mantecca, Luisa Fiandra

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Antibacterial and antioxidant activity of gold and silver nanoparticles in dextran-polyacrylamide copolymers.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Pamela FlorisPOLARIS Research Centre, Department of Earth and Environmental Sciences, University of Milano-Bicocca, 20126 Milan, Italy.ORCID 0000-0001-9813-985X
Stefania GarbujoDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy.
Gabriele RollaDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy.
Marco GiustraDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy.
Lucia SalvioniDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy.
Tiziano CatelaniMicroscopy Facility, University of Milano-Bicocca, 20126 Milan, Italy.
Miriam ColomboDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy.ORCID 0000-0003-3428-5668
Paride ManteccaPOLARIS Research Centre, Department of Earth and Environmental Sciences, University of Milano-Bicocca, 20126 Milan, Italy.ORCID 0000-0002-6962-049X
Luisa FiandraDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milan, Italy.
University of Milano-Bicocca · IT

Funding

Horizon 2020 Framework Programme 720851 PROTECTMinistero dell'Istruzione, dell'Università e della Ricerca Dipartimenti di Eccellenza 2017" - University of Milano Bicocca, Department of Biotechnology and Biosciences
6 · The paper itself

Abstract

In the biomedical field, gold nanoparticles (GNPs) have attracted the attention of the scientific community thanks to their high potential in both diagnostic and therapeutic applications. The extensive use of GNPs led researchers to investigate their toxicity, identifying stability, size, shape, and surface charge as key properties determining their impact on biological systems, with possible strategies defined to reduce it according to a Safe-by-Design (SbD) approach. The purpose of the present work was to analyze the toxicity of GNPs of various sizes and with different coating polymers on the developing vertebrate model, zebrafish. In particular, increasing concentrations (from 0.001 to 1 nM) of 6 or 15 nm poly-(isobutylene-alt-maleic anhydride)-

Indexed as

FETgold nanoparticlespolymeric-coatingsafe-by-designtoxicityzebrafish

Identifiers

PMID33919768
PMCPMC8070688
OpenAlexW3155272901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.