ArticleFoods (Basel, Switzerland)2021
Relationships between Structure and Antioxidant Capacity and Activity of Glycosylated Flavonols.
Article in Foods (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
46 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- Comparison of Antioxidant Capacity and Network Pharmacology of Phloretin and Phlorizin against Neuroinflammation in Traumatic Brain Injury.Molecules (Basel, Switzerland) · 2023Pooled it
- Comparative Effects of Quercetin and its α- and β-D-glucoside Derivatives in LPS-Stimulated C6 Astroglial Cells.Neurochemical research · 2026Article
- Untargeted Metabolomics Reveals Organ-Specific Metabolites Associated with Antioxidant and Anti-Inflammatory Activities in Finger Citron (Metabolites · 2026Article
- Species-Specific Metabolic Identities Persist in Fabaceae Callus Cultures Under Standardized Culture Conditions.Plants (Basel, Switzerland) · 2026Article
- Unveiling the Bioactive Potential of the Aerial Parts of BalkanPharmaceutics · 2026Article
- QSAR Analysis of Lichen Depsides and Derivatives: Electronic Descriptors as Predictors of Antioxidant Activity via PLS-1.Antioxidants (Basel, Switzerland) · 2026Article
- Enzymatic Modification of Flavonoids: Implications for Bioavailability, Bioactivity, and Therapeutic Potential Based on a Systematic Review and Bioinformatics Analysis.Antioxidants (Basel, Switzerland) · 2026Review
- Whole-GrainMolecules (Basel, Switzerland) · 2026Article
- Gluten-Free White Quinoa Flour Exhibits Antioxidant and Anti-Inflammatory Activity.Molecules (Basel, Switzerland) · 2026Article
- C-Ring Structure-Dependent Redox Properties of Flavonoids Regulate the Expression of Bioactivity.Antioxidants (Basel, Switzerland) · 2026Article
- Isolation, Antiradical Activity, and Cytotoxicity of Flavonoids From Cunila angustifolia.Chemistry & biodiversity · 2026Article
- Enzymatic preparation of epigallocatechin gallate diglucoside and bioactivity assessment.AMB Express · 2026Article
- Changes in nutritional and volatile composition of peach puree as affected by fermentation with differentFood chemistry: X · 2026Article
- Properties of Bisdiazo Compounds and Their Derived Carbenes via Density Functional Theory.Chemphyschem : a European journal of chemical physics and physical chemistry · 2026Article
- Flavonoids from mulberry leaves: physiological functions, molecular mechanisms and applications in juvenile animal health-A review.Frontiers in veterinary science · 2026Review
- Heat drastically alters floral color and pigment composition without affecting flower conspicuousness.American journal of botany · 2026Article
- Integrated metabolomics, network pharmacology and molecular docking to reveal the effects of drying processes on the antioxidant activity of mulberry (Frontiers in plant science · 2026Article
- The quercetin-serotonin transporter (SERT) connection: a new hope for depression therapy?Psychopharmacology · 2026Review
- Bioaccessibility of Phenolic Compounds and Antioxidant Capacity of Pulai (Preventive nutrition and food science · 2025Article
- Antitumoral effect of Nitraria retusa bioactive compounds on two glioblastoma cell lines.Human cell · 2025Article
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
The antioxidant capacity (AC) and antioxidant activity (AA) of three flavonols (FLV), aglycones and their glycosylated derivatives were evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays in various solvents. Findings confirmed that the glycosylation at the 3-position (3-glycosylation) always decreased the AC under most conditions due to substitution of the 3-position hydroxyl group and glycoside disruption in the molecular planarity. The 7-glycosylated derivatives did not have the above effects, thus generally exhibited ACs similar to their aglycones. Glycosylation decreased the AA of kaempferol and isorhamnetin for both assays in methanol, 3-glycosylation inhibited quercetin AA in the ABTS assay. In the DPPH assay, the AA of 3-glycosylated quercetin was significantly higher than quercetin. Using LC-MS/MS analysis, we found that quercetin and quercetin-7-glucoside underwent dimerization during the antioxidant reaction, potentially leading to a decline in AAs. However, 3-glycoside substitution may have hindered dimer formation, thereby allowing the FLVs to retain strong free radical scavenging abilities.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.