Evidence map›Paper›PMID 33919586›Full record

ArticleVaccines2021

COVID-19 Vaccination Scenarios: A Cost-Effectiveness Analysis for Turkey.

Arnold Hagens, Ahmet Çağkan İnkaya, Kasirga Yildirak, Mesut Sancar, Jurjen van der Schans, Aylin Acar Sancar, Serhat Ünal, Maarten Postma, Selen Yeğenoğlu

Abstract read
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Paid and unpaid productivity losses across 28 European countries due to excess deaths and COVID-19 deaths from 2020 to 2023.The European journal of health economics : HEPAC : health economics in prevention and care · 2026
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  11. Assessing the cost-effectiveness of COVID-19 vaccines in a low incidence and low mortality setting: the case of Thailand at start of the pandemic.The European journal of health economics : HEPAC : health economics in prevention and care · 2023
    Article
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  19. Anti-Biofilm and Antibacterial Activities ofAntibiotics (Basel, Switzerland) · 2022
    Article
  20. Value-based pricing of a COVID-19 vaccine.The Quarterly review of economics and finance : journal of the Midwest Economics Association · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Arnold HagensDepartment of Health Sciences, University Medical Center Groningen, University of Groningen (RUG), 9713 AV Groningen, The Netherlands.ORCID 0000-0002-9087-8719
Ahmet Çağkan İnkayaDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Hacettepe University, Ankara 06230, Turkey.ORCID 0000-0001-7943-8715
Kasirga YildirakDepartment of Actuarial Sciences, Faculty of Science, Hacettepe University, Ankara 06800, Turkey.
Mesut SancarDepartment of Clinical Pharmacy, Faculty of Pharmacy, Marmara University, Istanbul 34854, Turkey.
Jurjen van der SchansDepartment of Health Sciences, University Medical Center Groningen, University of Groningen (RUG), 9713 AV Groningen, The Netherlands.
Aylin Acar SancarPharmaceutical Care Unit, Faculty of Pharmacy, Marmara University, Istanbul 34854, Turkey.
Serhat ÜnalDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Hacettepe University, Ankara 06230, Turkey.
Maarten PostmaDepartment of Health Sciences, University Medical Center Groningen, University of Groningen (RUG), 9713 AV Groningen, The Netherlands.
Selen YeğenoğluDepartment of Pharmacy Management, Faculty of Pharmacy, Hacettepe University, Ankara 06230, Turkey.ORCID 0000-0002-5217-8797

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As of March 2021, COVID-19 has claimed the lives of more than 2.7 million people worldwide. Vaccination has started in most countries around the world. In this study, we estimated the cost-effectiveness of strategies for COVID-19 vaccination for Turkey compared to a baseline in the absence of vaccination and imposed measures by using an enhanced SIRD (Susceptible, Infectious, Recovered, Death) model and various scenarios for the first year after vaccination. The results showed that vaccination is cost-effective from a health care perspective, with an incremental cost-effectiveness ratio (ICER) of 511 USD/QALY and 1045 USD/QALY if vaccine effectiveness on transmission is equal or reduced to only 50% of effectiveness on disease, respectively, at the 90% baseline effectiveness of the vaccine. From a societal perspective, cost savings were estimated for both scenarios. Other results further showed that the minimum required vaccine uptake to be cost-effective would be at least 30%. Sensitivity and scenario analyses, as well as the iso-ICER curves, showed that the results were quite robust and that major changes in cost-effectiveness outcomes cannot be expected. We can conclude that COVID-19 vaccination in Turkey is highly cost-effective or even cost-saving.

Indexed as

cost-effectivenessCOVID-19dynamic modelingTurkeyvaccination

Identifiers

PMID33919586
PMCPMC8073609

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.