Evidence map›Paper›PMID 33919582›Full record

ArticleInternational journal of molecular sciences2021

Combinations of Piperine with Hydroxypropyl-β-Cyclodextrin as a Multifunctional System.

Anna Stasiłowicz, Natalia Rosiak, Ewa Tykarska, Maciej Kozak, Jacek Jenczyk, Piotr Szulc, Joanna Kobus-Cisowska, Kornelia Lewandowska, Anita Płazińska, Wojciech Płaziński and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Cyclodextrin-Based Systems ofMolecules (Basel, Switzerland) · 2025
    Article
  7. Improved Bioavailability of Stilbenes fromMolecules (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 1 country.

Anna StasiłowiczDepartment of Pharmacognosy, Faculty of Pharmacy, Poznan University of Medical Sciences, Swiecickiego 4, 60-781 Poznań, Poland.ORCID 0000-0001-5211-661X
Natalia RosiakDepartment of Pharmacognosy, Faculty of Pharmacy, Poznan University of Medical Sciences, Swiecickiego 4, 60-781 Poznań, Poland.ORCID 0000-0003-4722-6413
Ewa TykarskaDepartment of Chemical Technology of Drugs, Poznan University of Medical Sciences, Grunwaldzka 6, 60-780 Poznan, Poland.ORCID 0000-0001-9393-3536
Maciej KozakDepartment of Macromolecular Physics, Faculty of Physics, Adam Mickiewicz University, Uniwersytetu Poznańskiego 2, 61-614 Poznań, Poland.ORCID 0000-0003-3312-6518
Jacek JenczykNanoBioMedical Centre, Adam Mickiewicz University, Wszechnicy Piastowskiej 3, 61-614 Poznań, Poland.ORCID 0000-0003-1700-6719
Piotr SzulcDepartment of Agronomy, Poznań University of Life Sciences, Dojazd 11, 60-632 Poznań, Poland.ORCID 0000-0002-9670-3231
Joanna Kobus-CisowskaDepartment of Gastronomy Sciences and Functional Foods, Faculty of Food Science and Nutrition, Poznań University of Life Sciences, Wojska Polskiego 31, 60-624 Poznań, Poland.ORCID 0000-0003-2834-0405
Kornelia LewandowskaInstitute of Molecular Physics, Polish Academy of Sciences, Smoluchowskiego 17, 60-179 Poznan, Poland.ORCID 0000-0002-2063-7805
Anita PłazińskaDepartment of Biopharmacy, Faculty of Pharmacy, Medical University of Lublin, Chodzki 4a, 20-093 Lublin, Poland.ORCID 0000-0002-3698-2574
Wojciech PłazińskiJerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences, Niezapominajek 8, 30-239 Krakow, Poland.ORCID 0000-0003-1427-8188
Judyta Cielecka-PiontekDepartment of Pharmacognosy, Faculty of Pharmacy, Poznan University of Medical Sciences, Swiecickiego 4, 60-781 Poznań, Poland.ORCID 0000-0003-0891-5419
Poznan University of Medical Sciences · PLAdam Mickiewicz University in Poznań · PLUniversity of Life Sciences in Poznań · PLInstitute of Molecular Physics of the Polish Academy of Sciences · PLJerzy Haber Institute of Catalysis and Surface Chemistry, Polish Academy of Sciences · PLMedical University of Lublin · PL

Funding

Narodowe Centrum Nauki UMO-2020/37/B/NZ7/03975
6 · The paper itself

Abstract

Piperine is an alkaloid that has extensive pharmacological activity and impacts other active substances bioavailability due to inhibition of CYP450 enzymes, stimulation of amino acid transporters and

Indexed as

2-Hydroxypropyl-beta-cyclodextrinAlkaloidsAnimalsBenzodioxolesBlood-Brain BarrierCalorimetry, Differential ScanningHumansPiperidinesPolyunsaturated AlkamidesSolubilitySpectroscopy, Fourier Transform InfraredX-Ray Diffraction2-Hydroxypropyl-beta-cyclodextrinAlkaloidsBenzodioxolesPiperidinespiperinePolyunsaturated Alkamidesanti-inflammatory and neuroprotective activityhydroxypropyl-β-cyclodextrinpermeabilitypiperinesolubility

Identifiers

PMID33919582
PMCPMC8072981
OpenAlexW3155660695

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.