Evidence map›Paper›PMID 33919572›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Dual Effect of

Salvatore Mazzeo, Valentina Bessi, Silvia Bagnoli, Giulia Giacomucci, Juri Balestrini, Sonia Padiglioni, Giulia Tomaiuolo, Assunta Ingannato, Camilla Ferrari, Laura Bracco and 2 more

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05569083 (PRedicting the EVolution of SubjectIvE Cognitive Decline to Alzheimer's Disease With Machine Learning), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05569083 unknown statusnot on this map

PRedicting the EVolution of SubjectIvE Cognitive Decline to Alzheimer's Disease With Machine Learning

TypeobservationalSponsorAzienda Ospedaliero-Universitaria CareggiRan2020 to 2024Enrolled350ConditionsCognitive Decline, Mild Cognitive Impairment, Alzheimer DiseaseArmsGenetic analysis of APOE and BDNF genes., EEG recording, CSF collection and AD biomarker measurement, Neuropsychological evaluation, Assessment of cognitive reserve, depression, personality traits and leisure activities
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Salvatore MazzeoDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.ORCID 0000-0001-5985-5060
Valentina BessiDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.ORCID 0000-0002-6176-3584
Silvia BagnoliDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.
Giulia GiacomucciDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.ORCID 0000-0002-8711-331X
Juri BalestriniDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.
Sonia PadiglioniRegional Referral Centre for Relational Criticalities, 50134 Tuscany Region, Italy.
Giulia TomaiuoloDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.ORCID 0000-0001-7062-3797
Assunta IngannatoDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.
Camilla FerrariDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.
Laura BraccoDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.
Sandro SorbiDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.
Benedetta NacmiasDepartment of Neuroscience, Psychology, Drug Research and Child Health, University of Florence, 50134 Florence, Italy.
University of Florence · ITDon Carlo Gnocchi Foundation · ITAzienda Ospedaliero-Universitaria Careggi · IT

Funding

Fondazione Cassa di Risparmio di Firenze 2015.0713Tuscany Region 20RSVB
6 · The paper itself

Abstract

backgroundPeriodic circadian protein homolog 2 (

methodsForty-five SCD patients were included in this study. All participants underwent extensive neuropsychological investigation, analysis of apolipoprotein E (

resultsNine out of 45 patients (20%) were heterozygous carriers of the

conclusions

Indexed as

Alzheimer’s diseasecognitive reserveexecutive functionlanguageneuropsychologyPER2 genesubjective cognitive declinevisual–spatial ability

Identifiers

PMID33919572
PMCPMC8074126
OpenAlexW3154207079

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.