ArticleJournal of clinical medicine2021
Left Ventricle Structure and Function in Young Adults Born Very Preterm and Association with Neonatal Characteristics.
Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 18 citations in OpenAlex.
- From Neonatal History to Adult Cardiovascular Risk: Preterm Birth as a Lifelong Risk Enhancer.Medical sciences (Basel, Switzerland) · 2026Review
- Cardiac function in 6-year-old children born extremely preterm and associations to prolonged patent ductus arteriosus shunting.Scientific reports · 2026Article
- Cardiac function at follow-up in infants treated with therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy.Pediatric research · 2025Article
- Impact of Preterm Birth on Long-Term Cardiac Function: A Comprehensive Echocardiographic Study in School-Aged Children.Medicina (Kaunas, Lithuania) · 2025Article
- Cardiovascular Health Starts in the Womb.Hypertension (Dallas, Tex. : 1979) · 2024Review
- Smaller Left Ventricular Size But Preserved Function in Adolescents and Adults Born Preterm.Journal of the American Heart Association · 2024Article
- Impact of prematurity on lifelong cardiovascular health: structural and functional considerations.NPJ cardiovascular health · 2024Review
- Early cardiac function and death, severe bronchopulmonary dysplasia and pulmonary hypertension in extremely preterm infants.Pediatric research · 2024Article
- Differing Impact of Preterm Birth on the Right and Left Atria in Adulthood.Journal of the American Heart Association · 2022Article
- Understanding the preterm human heart: What do we know so far?Anatomical record (Hoboken, N.J. : 2007) · 2022Review
- Cardiac Left Ventricle Mitochondrial Dysfunction After Neonatal Exposure to Hyperoxia: Relevance for Cardiomyopathy After Preterm Birth.Hypertension (Dallas, Tex. : 1979) · 2022Article
Corrections and comments
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Authors and funding
17 authors at 4 institutions in 1 country.
Funding
Abstract
Preterm birth increases risk of cardiovascular disease and early death. A body of evidence suggests left ventricle (LV) echocardiographic alterations in children and adults born preterm. We aimed to determine if neonatal characteristics were associated with alterations in LV structure and function in preterm adults. We evaluated a cohort of 86 young adults born preterm below 30 weeks of gestation, and 85 full-term controls. We determined LV dimensions and function using tissue Doppler imaging, conventional and speckle tracking echocardiography (STE). Adults born preterm had smaller LV dimensions, but these differences did not remain after adjustment for body surface area (BSA), which was smaller in the preterm group. Stroke volume and cardiac output were reduced even after adjustment for BSA. We found a smaller e' wave in the preterm group, but other markers of systolic and diastolic function did not differ. Use of antenatal steroids may be associated with a further reduced cardiac output in those born preterm. Adults born preterm show alterations in markers of LV dimensions and function. Identification of these markers may represent opportunities for early prevention of cardiovascular events in this at-risk population.
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Registered trials
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