Evidence map›Paper›PMID 33919494›Full record

ArticleJournal of clinical medicine2021

PEComa-A Rare Liver Tumor.

Marek Krawczyk, Bogna Ziarkiewicz-Wróblewska, Tadeusz Wróblewski, Joanna Podgórska, Jakub Grzybowski, Beata Gierej, Piotr Krawczyk, Paweł Nyckowski, Oskar Kornasiewicz, Waldemar Patkowski and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  3. [Misdiagnosis of a giant hepatic perivascular epithelioid cell tumor: A case report].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Marek KrawczykDepartment of General, Transplant and Liver Surgery, Medical University Warsaw, 02-097 Warsaw, Poland.
Bogna Ziarkiewicz-WróblewskaDepartment of Pathology, Medical University of Warsaw, 02-097 Warsaw, Poland.
Tadeusz WróblewskiDepartment of General, Transplant and Liver Surgery, Medical University Warsaw, 02-097 Warsaw, Poland.
Joanna Podgórska2nd Department of Clinical Radiology, Medical University of Warsaw, 02-097 Warsaw, Poland.
Jakub GrzybowskiDepartment of Pathology, Medical University of Warsaw, 02-097 Warsaw, Poland.
Beata GierejDepartment of Pathology, Medical University of Warsaw, 02-097 Warsaw, Poland.
Piotr KrawczykDepartment of General, Transplant and Liver Surgery, Medical University Warsaw, 02-097 Warsaw, Poland.
Paweł NyckowskiDepartment of General, Gastroenterological and Oncological Surgery, Medical University Warsaw, 02-097 Warsaw, Poland.
Oskar KornasiewiczDepartment of General, Transplant and Liver Surgery, Medical University Warsaw, 02-097 Warsaw, Poland.
Waldemar PatkowskiDepartment of General, Transplant and Liver Surgery, Medical University Warsaw, 02-097 Warsaw, Poland.
Piotr RemiszewskiDepartment of General, Transplant and Liver Surgery, Medical University Warsaw, 02-097 Warsaw, Poland.
Krzysztof ZającDepartment of General, Transplant and Liver Surgery, Medical University Warsaw, 02-097 Warsaw, Poland.
Michał GrątDepartment of General, Transplant and Liver Surgery, Medical University Warsaw, 02-097 Warsaw, Poland.ORCID 0000-0003-3372-3072
Medical University of Warsaw · PL

Funding

Ministerstwo Nauki i Szkolnictwa Wyższego 571/STYP/14/2019
6 · The paper itself

Abstract

PEComa (perivascular epithelioid cell tumor) is a rare liver tumor. Decisions regarding patient management are currently based on a few small case series. The aim of this study was to report the clinicopathological features of PEComa in order to provide guidance for management, complemented by our own experience. This retrospective observational study included all patients with PEComa who underwent surgical treatment in two departments between 2002 and 2020. A total of 20 patients were diagnosed with PEComa following histopathological examination. The age of the patients ranged from 21 to 73 years. The majority of patients were women (85%). In most patients, the tumors were incidental. In diagnostic studies, PEComas with high arterial vascularization have been described. Liver resection was the treatment of choice. There was only one postoperative complication. During histopathological evaluation, tumors were composed mostly of epithelioid cells, rarely with spindle cell components, thick-walled vessels, and adipocytes in different proportions. Melanocytic markers (HMB45, MelanA) and at least one smooth muscle marker were expressed in all tumors. Features suggestive of malignancy were found in three cases. In conclusion, PEComa is a rare liver tumor that is usually diagnosed incidentally. In radiological studies, tumors with high arterial vascularization are observed. Liver resection is the treatment of choice.

Indexed as

angiomyolipomahistopathologyliver resectionmanagementmesenchymal tumorPEComaperivascular epithelioid cell tumorrare liver tumorsurgery

Identifiers

PMID33919494
PMCPMC8072725
OpenAlexW3155240658

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.